Identification of breast cancer in patients with pathologic nipple discharge: does ductoscopy predict malignancy? - 18/08/11
Corresponding author. University Hospitals of Cleveland, 11100 Euclid Ave., Cleveland, OH 44106-5047. Tel.: +1-216-844-8247; fax: +1-216-844-5957.Abstract |
Objective |
The purpose of the current study was to review characteristics of patients with nipple discharge who underwent ductoscopy-assisted excisional biopsy who had a final diagnosis of carcinoma.
Methods |
A retrospective review was performed of patients presenting with pathologic nipple discharge (PND) who underwent ductoscopy-assisted excisional biopsy and had a final diagnosis of carcinoma.
Results |
A total of 14 (7%) of 188 patients who underwent ductoscopy-assisted excision had a final pathology of ductal carcinoma-in-situ (DCIS) (12/14, 86%) or invasive breast cancer with DCIS (2/14, 14%). Duct wall irregularities or intraluminal growths were visualized during ductoscopy in 8 of the 14 (57%) breast cancer patients. There were no visual abnormalities noted during ductoscopy that accurately predicted a final diagnosis of malignancy.
Conclusions |
Although occult malignancies can be identified in patients undergoing ductoscopy-assisted biopsy for PND, no clear morphologic changes visualized during ductoscopy definitively indicated the presence of malignancy.
Le texte complet de cet article est disponible en PDF.Keywords : Pathologic nipple discharge, Ductal lavage, Ductoscopy, Optical interrogation
Plan
Vol 192 - N° 4
P. 530-533 - octobre 2006 Retour au numéro
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