Comparison of Coronary Minimal Lumen Area Quantification by Sixty-Four–Slice Computed Tomography Versus Intravascular Ultrasound for Intermediate Stenosis - 17/08/11
, Christophe Larchez, MD b, Saïd Ghostine, MD a, David Pesenti-Rossi, MD a, Béatrice Daoud, MD b, Michel Habis, MD a, Anne Sigal-Cinqualbre, MD b, Eric Perrier, MD c, Claude-Yves Angel, MD b, Bernard Lancelin, MD a, Jean-François Paul, MD b
Corresponding author: Tel: 33-1-4094-2800; fax: 33-1-4094-8549.Résumé |
The present study assessed 64-slice computed tomographic accuracy to quantify minimal lumen area (MLA) and determine lesion severity in intermediate stenosis by angiography compared with intravascular ultrasound (IVUS). Sixty-four–slice computed tomography (CT) has been shown to be effective in coronary stenotic assessment by visual estimation compared with angiography. However, angiography is not an accurate gold standard for intermediate stenotic quantification compared with IVUS. Forty patients (54 lesions) with 30% to 70% coronary stenosis by angiography in a major coronary branch were included. All patients underwent quantitative angiography, retrospective electrocardiographically gated 64-slice CT (Siemens), and IVUS (40-MHz Atlantis; Boston Scientific). MLA was manually traced by 2 blinded and independent operators on 64-slice computed tomographic cross-sectional reconstruction and compared with IVUS MLA. A lesion was considered significant if the MLA was ≤6 mm2 for the left main coronary artery and ≤4 mm2 for another epicardial vessel with CT and IVUS. The correlation between IVUS MLA and computed tomographic MLA was r = 0.88 (p <0.001). Interobserver variabilities (mean ± SD) were 1.2 mm2 for CT and 1.1 mm2 for CT versus IVUS. Bland-Altman analysis showed a 95% confidence interval of −42% to +44% for computed tomographic measurement using IVUS as a reference. Sensitivity, specificity, accuracy, and Cohen’s κ coefficient for significant lesion classification using CT were 87%, 72%, 80%, and 0.6, respectively (p <0.0001). In conclusion, when using MLA, 64-slice CT was able to quantify coronary stenosis with good correlation compared with IVUS and determine lesion severity in patients with intermediate lesions by angiography.
Le texte complet de cet article est disponible en PDF.Plan
Vol 98 - N° 7
P. 871-876 - octobre 2006 Retour au numéro
Article précédent
- Usefulness of Follow-Up Low-Density Lipoprotein Cholesterol Level as an Independent Predictor of Changes of Coronary Atherosclerotic Plaque Size as Determined by Intravascular Ultrasound Analysis After Statin (Atorvastatin or Simvastatin) Therapy
- Myeong-Ki Hong, Cheol Whan Lee, Young-Hak Kim, Duk-Woo Park, Se-Whan Lee, Chang-Bum Park, Jae-Sik Jang, Ki-Hoon Han, Sang-Sig Cheong, Jae-Joong Kim, Seong-Wook Park, Seung-Jung Park
- Comparison of Sixty-Four–Slice Multidetector Computed Tomographic Coronary Angiography to Coronary Angiography With Intravascular Ultrasound for the Detection of Transplant Vasculopathy
- Shawn A. Gregory, Maros Ferencik, Stephan Achenbach, Robert W. Yeh, Udo Hoffmann, Ignacio Inglessis, Ricardo C. Cury, Koen Nieman, Iris A. McNulty, Josephine A. Laffan, Eugene V. Pomerantsev, Thomas J. Brady, Marc J. Semigran, Ik-Kyung Jang
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?