Endoscopic plication of massively bleeding peptic ulcer by using the Eagle Claw VII device: a feasibility study in a porcine model - 17/08/11
Reprint requests: Philip W.Y. Chiu, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, 30-32, Ngan Shing St, Shatin, Hong Kong.Hong Kong; Port Moresby, Papua New Guinea
Abstract |
Background and Objective |
We examined the efficacy of endoscopic plication when using Eagle Claw VII in a porcine bleeding ulcer model.
Animal Model Preparation |
The right gastroepiploic artery (diameter 1.5-2 mm) was isolated and was tunneled to small gastrotomies at either the lesser or greater curvature of the stomach.
Interventions |
We applied the Eagle Claw VII to achieve hemostasis.
Main Outcome Measurements |
The survival of the pigs after endoscopic plication for hemostasis, time to achieve hemostasis with Eagle Claw VII, recurrent bleeding, number of successful plication, and number of suture remained.
Results |
Endoscopic plication was performed on bleeding gastric ulcers in 6 pigs. The time to achieve hemostasis was 6 minutes 56 seconds ± 3 minutes 50 seconds. There was no complication. A total of 14 plications were performed. All animals survived for 1 week without recurrent bleeding. At the postmortem, 10 of the plication sutures remained.
Limitation |
Our model cannot simulate the chronicity of peptic ulcer.
Conclusions |
In this porcine model, the Eagle Claw VII effectively stopped bleeding from arteries 2 mm in size.
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| The funding of this study is supported by the Endoscopy Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong. |
Vol 63 - N° 4
P. 681-685 - avril 2006 Retour au numéro
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