Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis - 16/08/11
Corresponding author. Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, 7 Chung-Shan South Road, Taipei 100, Taiwan. Tel.: +886 2 3123456x5363.Summary |
We present a diabetic patient with necrotizing fasciitis caused by Citrobacter freundii associated with an injury from the fish fin. Two isolates recovered six days after cefotaxime treatment had a cefotaxime minimum inhibitory concentration (MIC) of 0.12 and 256mg/L, respectively, and a cefepime MIC of 0.03 and 0.25mg/L, respectively. The two isolates both possessed blaCMY-2 gene. The patient responded unsatisfactorily to cefotaxime and cefepime therapy and surgical debridement but recovered completely after ertapenem treatment for 42 days.
Le texte complet de cet article est disponible en PDF.Keywords : Necrotizing fasciitis, Citrobacter freundii, blaCMY-2 gene ertapenem
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Vol 53 - N° 3
P. e161-e163 - septembre 2006 Retour au numéro
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