Tramadol Improves Patients’ Tolerance of Transrectal Ultrasound-Guided Prostate Biopsy - 15/08/11
, Alexander Kaploun b, Gazy Faris b, Boaz Appel b, Ilia Shneider a, Avi Stein b, Reuven Pizov a
Reprint requests: Irina Hirsh, M.D., Department of Anesthesiology and Critical Care Medicine, Lady Davis Carmel Medical Center, 7 Michal Street, Haifa 34362, Israel.Résumé |
Objectives |
To evaluate the analgesic advantage of tramadol in patients undergoing transrectal biopsy of the prostate in ambulatory settings compared with topical analgesia.
Methods |
A total of 77 patients scheduled for prostate biopsy were randomly assigned to receive 5% lidocaine ointment 5 mL per rectum 10 minutes before the procedure (group 1) or lidocaine ointment combined with tramadol drops 1 mg/kg per os 40 minutes before the procedure (group 2). Pain severity, main cardiorespiratory parameters, difficulty of the procedure, procedure-related side effects, and complications were analyzed.
Results |
No significant respiratory or hemodynamic disturbances were observed. The pain severity, as measured on a visual analog scale, was significantly lower in group 2 (P = 0.038), and the rate of overall satisfaction with the level of analgesia was significantly greater (P = 0.027). The urologist’s assessment of “very easy” was assigned to 77.1% of procedures in group 2 compared with 54.8% of procedures in group 1 (P = 0.04). The rate of side effects in both groups was similar at 9.5% versus 11.4% (P = 0.785).
Conclusions |
The combination of lidocaine per rectum with tramadol per os is a simple and safe technique providing good analgesic effect and, therefore, can be recommended for transrectal ultrasound-guided prostate biopsy.
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| The present study was solely supported by the Lady Davis Carmel Medical Center, and no extra-institutional funding was accepted. |
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| The authors affirm that no funding agreement limited their ability fairly to complete and publish their research, and that they had full control of primary data. |
Vol 69 - N° 3
P. 491-494 - mars 2007 Retour au numéro
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