Chemotactic Factors Associated with Eosinophilic Gastrointestinal Diseases - 12/08/11
Doi : 10.1016/j.iac.2008.10.002
Carine Blanchard, PhD, Marc E. Rothenberg, MD, PhD ⁎ 
Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, MLC 7028, Cincinnati, OH 45229–3039, USA
Corresponding author.Abstract |
The gastrointestinal (GI) tract is in constant negotiation with the microbial flora present in the lumen. Resident hematopoietic cells (ie, lymphocytes, mast cells, and eosinophils) are part of this ongoing and silent homeostatic battle. Eosinophilic GI diseases are characterized by an increased number of eosinophil infiltrates with no identified cause. This article describes the past and present knowledge regarding the chemotactic factors involved in GI eosinophilia.
Le texte complet de cet article est disponible en PDF.Keywords : Eosinophil, Gastrointestinal, Chemokine, Cytokine, Pathogenesis
Plan
| This work was supported by in part by the American Heart Association 0625296B (CB); the Thrasher Research Fund NR-0014 (CB); the PHS Grant P30 DK0789392 (CB); the NIH AI079874-01 (CB), AI070235, AI45898, and DK076893 (MER); the Food Allergy and Anaphylaxis Network (MER); Campaign Urging Research for Eosinophil Disorders; the Buckeye Foundation (MER); and the Food Allergy Project (MER). |
© 2009
Elsevier Inc. Tous droits réservés.
Vol 29 - N° 1
P. 141-148 - février 2009 Retour au numéro
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