Assessing response to changing plasma/red cell ratios in a bleeding trauma patient - 12/08/11
Abstract |
Recent military experience suggests that transfusing fresh frozen plasma and packed red cells in a 1:1 ratio may improve survival in exsanguinating trauma patients. We report the case of a single patient who required massive transfusion after suffering a single gunshot wound. Initially, the patient received FFP:PRBC in 1:2 ratio, but this did not correct laboratory parameters except for INR and clotting factor VII level, which were likely normalized by treatment with recombinant activated factor VII. After receiving FFP:PRBC in a 4:5 ratio, he continued to bleed and his coagulation profile showed no appreciable improvement. In the final phase, he received FFP:PRBC in a 7:5 ratio and his laboratory parameters of coagulopathy normalized, except for factor V level which was improved. He also clinically stopped bleeding.
Le texte complet de cet article est disponible en PDF.☆ | This study was supported through the Military Health Services Research Grant from the Canadian Forces Health Services and through the financial support of the Defence Research and Development Canada. |
☆☆ | SR receives salary support from the combined partnership of the Canadian Institute of Health Research and Novo Nordisk. |
★ | Both HT and SR had full access to all data in this study and take responsibility for the integrity of the data and for the accuracy of its analysis. |
Vol 28 - N° 1
P. 120.e1-120.e5 - janvier 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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