Monday preference in onset of takotsubo cardiomyopathy - 12/08/11
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for the Takotsubo Italian Network investigators
Abstract |
Objective |
Acute cardiovascular events show definite temporal patterns of occurrence. Takotsubo cardiomyopathy (TTC) has been recently shown to exhibit a seasonal (summer) and circadian (morning) temporal distribution. The aim of this study, based on the database of a multicenter Italian network, was to investigate the possible existence of a weekly pattern of onset of TTC.
Methods |
The study included all cases of TTC admitted to the coronary care unit of 8 referral cardiac centers in Italy (five in Southern Italy and three in Northern Italy, respectively), belonging to the Takotsubo Italian Network (January 2002-December 2008). Day of admission was categorized into seven 1-day intervals according by week, and chronobiological analysis was performed by partial Fourier series.
Results |
The database included 112 patients with TTC (92.9% females). The weekly distribution identified the highest number of cases on Monday and the lowest on Saturday. Chronobiologic analysis yielded a rhythmic pattern with a significant peak on Monday (P = .036).
Conclusions |
This study confirms a Monday preference for TTC occurrence on Monday, similar to that reported for acute myocardial infarction. Stress of starting weekly day life activities, could play a triggering role.
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☆ | Funding support: supported, in part, by a scientific grant “Finanziamento per ricerca locale - FAR” from the University of Ferrara, Italy. |
Vol 28 - N° 6
P. 715-719 - juillet 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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