1. Lymphocytes - 12/08/11
Reprint requests: Jordan S. Orange, MD, PhD, Children’s Hospital of Philadelphia, Division of Immunology, 3615 Civic Center Blvd, ARC-1016H, Philadelphia, PA 19104.This activity is available for CME credit. See page 5A for important information.
Abstract |
Lymphocytes are white blood cells uniform in appearance but varied in function and include T, B, and natural killer cells. These cells are responsible for antibody production, direct cell-mediated killing of virus-infected and tumor cells, and regulation of the immune response. Advances in immunology have led to the characterization of newly appreciated effector populations such as IL-17–producing T cells, T cells with regulatory function, and natural killer T cells, thus revising established paradigms. This chapter provides an overview of the major lymphocyte populations with emphasis on their development, distinguishing characteristics, and functions.
Le texte complet de cet article est disponible en PDF.Key words : Lymphocyte, adaptive immune system, T cell, B cell, natural killer cell
Abbreviations used : APC, BCR, CSR, D, DC, DP, GC, iNKT, ITAM, J, NK, nTreg, SHM, TCM, TEM, TCR, Treg, V
Plan
| Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest. |
Vol 121 - N° 2S2
P. S364-S369 - février 2008 Retour au numéro
Article précédent
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