Transient Neonatal Hypothyroidism is Associated with Elevated Serum Anti-Thyroglobulin Antibody Levels in Newborns and Their Mothers - 11/08/11
Doi : 10.1016/j.jpeds.2006.11.034
Arash Ordookhani, MD a, ⁎ 
, Parvin Mirmiran, PhD a, Paul G. Walfish, CM, MD b, Fereidoun Azizi, MD a
, Parvin Mirmiran, PhD a, Paul G. Walfish, CM, MD b, Fereidoun Azizi, MD a a Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
b Endocrine Division, Department of Medicine, Mount Sinai Hospital, University of Toronto Medical School, Toronto, Ontario, Canada.
Reprint requests: Dr Arash Ordookhani, Endocrine Research Center, Taleghani Hospital, Evin Avenue, Tehran, Iran. P.O. Box: 19395-4763.Résumé |
Transient congenital hypothyroidism (TCH) was detected in 6 of 35,067 newborns (1:5845 births) screened in Iran. Antithyroglobulin antibodies positivity was present in 4 of 6 (66.7%) of those with TCH and in 6 of 106 (5.7%) of those with “transient hyperthyrotropinemia and normal” diagnoses (P = .0005), but positivity was similar in newborns with transient hyperthyrotropinemia versus normal neonates (P = .397).
Le texte complet de cet article est disponible en PDF.Abbreviations : CH, T4, TCH, TgAb, THAb, THT, TPOAb, TRAb, TSH, UIC, US
Plan
| This study was supported partly by grant no. 115 NRCI of the National Research Council of the I.R. Iran and partly by a grant from the Endocrine Research Center, Shaheed Beheshti University of Medical Sciences. |
© 2007
Mosby, Inc. Tous droits réservés.
Vol 150 - N° 3
P. 315 - mars 2007 Retour au numéro
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