Assessment of Likelihood of Submucosal Invasion in Non-Polypoid Colorectal Neoplasms - 11/08/11

Doi : 10.1016/j.giec.2010.03.007

Takahisa Matsuda, MD, PhD ^a,^⁎ , Adolfo Parra-Blanco, MD, PhD ^b, Yutaka Saito, MD, PhD ^a, Taku Sakamoto, MD ^a, Takeshi Nakajima, MD, PhD ^a
^a Endoscopy Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
^b Department of Gastroenterology, Central University Hospital of Asturias, Celestino Villamil s/n, 33006 Oviedo, Principado de Asturias, Oviedo, Spain

Corresponding author.

Résumé

Although of lower prevalence compared with polypoid neoplasms, the non-polypoid neoplasms, especially the depressed type, are important to diagnose because they belong to a distinct biologically aggressive subset, given the high rate of intramucosal or submucosal cancers. The detection and diagnosis of the non-polypoid colorectal neoplasm presents a challenge and an opportunity. Above all, characteristic colonoscopic findings obtained by a combination of conventional colonoscopy and magnifying chromoendoscopy are useful for determination of the invasion depth of non-polypoid colorectal cancers, an essential factor in selecting a treatment modality.

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Keywords : Non-polypoid colorectal neoplasm, Submucosal cancer, Lymph node metastasis, Endoscopic diagnosis, Magnifying chromoendoscopy