Diagnostic testing and interpretation of tests for autoimmunity - 11/08/11
, Mark Gourley, MD
Reprint requests: Christine Castro, DO, National Institutes of Health, Building 10, CRC, Room 5, SEN–5-3481, Bethesda, MD 20892.Abstract |
Laboratory testing is of great value when evaluating a patient with a suspected autoimmune disease. The results can confirm a diagnosis, estimate disease severity, aid in assessing prognosis and are useful for following disease activity. Components of the laboratory examination include a complete blood count with differential, a comprehensive metabolic panel, measurement of inflammatory markers and autoantibodies, and flow cytometry. This chapter discusses these components and includes a discussion about organ-specific immunologic diseases for which immunologic laboratory testing is used. Comprehensive laboratory evaluation of a suspected autoimmune illness in conjunction with a thorough clinical evaluation provides a better understanding of a patient’s immunologic disease.
Le texte complet de cet article est disponible en PDF.Key words : Autoimmune, disease, laboratory, inflammatory markers, evaluation, rheumatic, serologies, flow cytometry, HLA, organ specific
Abbreviations used : ACE, AIHA, ALT, ANA, ANCA, Anti-GBM, aPL, APS, AST, cANCA, CBC, CCP, CH50, CK, CRP, CSS, DM, dsDNA, ESR, IBM, IIM, JIA, LDH, MPA, MPO, pANCA, PM, PR3, RA, RBC, RF, RIA, RNP, SLE, SRP, WBC, WG
Plan
| Disclosure of potential conflict of interest: The authors have declared that they have no conflict of interest. |
Vol 125 - N° 2S2
P. S238-S247 - février 2010 Retour au numéro
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