Advances in adult asthma diagnosis and treatment and HEDQ in 2010 - 10/08/11
Reprint requests: Andrea J. Apter, MD, MSc, 829 Gates Building, Hospital of the University of Pennsylvania, 3600 Spruce St, Philadelphia, PA 19104.Abstract |
This summary reviews research published over the past year on asthma and through the prism of health care delivery and quality. Special attention is given to management, therapeutics, and the role of environmental exposures and their interactions with genetics. The discussion is framed around the 3 stages of translational research: from bench to first studies in human subjects, then to larger efficacy studies in well-defined patient populations, and finally into practice through effectiveness research in real-world settings.
Le texte complet de cet article est disponible en PDF.Key words : Asthma, adults, genetics, inhaled corticosteroids, biomarkers, long-acting β-agonist, tiotropium, anti–IL-5, translational research, comparative effectiveness research
Abbreviations used : AIM, ACT, CAMP, CER, COPD, ED, FeNO, GWAS, HEDQ, ICS, LABA, SNP
Plan
| Disclosure of potential conflict of interest: A. J. Apter has received research support from the National Institutes of Health/National Heart, Lung, and Blood Institute. |
Vol 127 - N° 1
P. 116-122 - janvier 2011 Retour au numéro
Article précédent
- Advances in pediatric asthma in 2010: Addressing the major issues
- Stanley J. Szefler
- A call for action: Comparative effectiveness research in asthma
- Jerry A. Krishnan, Michael Schatz, Andrea J. Apter
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