Catch-down growth during infancy of children born small (SGA) or appropriate (AGA) for gestational age with short-statured parents - 10/08/11
Reprint requests: Helmuth G. Dörr, MD, Division of Pediatric Endocrinology, Hospital for Children and Adolescents, Friedrich-Alexander-University of Erlangen-Nuremberg, Loschgestrasse 15, 91054 Erlangen, GermanyRésumé |
Objective |
We analyzed postnatal growth in children with familial short stature (FSS) with regard to small (SGA) or appropriate (AGA) for gestational age status at birth.
Study design |
We studied 96 otherwise healthy short-statured children (58 males; SGA: n = 41, AGA: n = 55). At least one of the parents was short-statured. Cross-sectional data for length/height and weight for the first 4 years of age were collected retrospectively.
Results |
AGA children had a mean length of 0.09 ± 1.02 standard deviation score (SDS) at birth, −1.57 ± 1.16 SDS after 1 year of age, and −2.36 ± 0.72 SDS after 4 years. SGA children had a mean length of −2.04 ± 1.06 SDS at birth, −2.70 ± 1.12 SDS at 1 year of age, and −3.05±0.86 SDS at 4 years. The loss of length SDS within the first 2 years of life was greater in AGA than in SGA children. SGA children were significantly shorter than AGA children at all of the study points (p <.001).
Conclusions |
Children with an FSS background born AGA show catch-down growth to their lower familial range during the first 2 years of life. SGA children did not catch up to their AGA peers at any time.
Le texte complet de cet article est disponible en PDF.Abbreviations : AGA, BMI, f, FSS, IGF, ISS, m, SDS, SGA
Plan
Vol 148 - N° 6
P. 747-752 - juin 2006 Retour au numéro
Article précédent
- Respiratory distress syndrome-associated inflammation is related to early but not late peri/intraventricular hemorrhage in preterm infants
- Tannette G. Krediet, Annemieke Kavelaars, Hendrik J. Vreman, Cobi J. Heijnen, Frank van Bel
- Homozygosity for TNSALP mutation 1348c>T (Arg433Cys) causes infantile hypophosphatasia manifesting transient disease correction and variably lethal outcome in a kindred of black ancestry
- Michael P. Whyte, Kevan Essmyer, Michael Geimer, Steven Mumm
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?