Smaller mandibular size in infants with a history of an apparent life-threatening event - 09/08/11
, Daniel D. Kinnamon, MS, Nalton Ferraro, DMD, MD, Martha A.Q. Curley, RN, PhD, FAAN
Reprint requests: Mary Horn; 10S; Children’s Hospital Boston; 300 Longwood Ave; Boston, MA 02115.Résumé |
Objectives |
To examine small mandibular size and preference for a hand-to-chin posture as salient characteristics in infants with a history of an apparent life-threatening event (ALTE).
Study design |
This was a prospective case-control study of term infants, from birth to 6 months of age, admitted post-ALTE and matched 1:2 with healthy control infants (age within 2 weeks and weight within 0.5 kg). Infants with confirmed gastroesophageal reflux and congenital anomalies, including severe micrognathia, were excluded.
Results |
Infants with a history of an ALTE (n = 25) were matched to 47 healthy controls. Infants with a history of an ALTE had mandibular indices (larger index indicates a smaller mandible) that were 3.8 mm greater on the left side (95% CI: 2.0-5.6, P < .001) and 4.2 mm greater on the right side (95% CI: 2.7-5.6, P < .001) adjusting for length and non-white race. Controlling for matching and length, a 1-mm increase in the average mandibular index increased the odds of an ALTE by 62% (OR = 1.62, 95% CI: 1.22-2.44, P < .001).
Conclusions |
Smaller mandibular size was associated with ALTE, suggesting airway obstruction as a potential cause of ALTE. The association of this characteristic with ALTE also offers the potential for prospective quantification of ALTE risk.
Le texte complet de cet article est disponible en PDF.Abbreviations : ALTE, CPR, GN, N, OBI, OSA, SIDS
Plan
| Supported by the Center for Nursing, Children’s Hospital, Boston; The Thoracic Foundation. |
Vol 149 - N° 4
P. 499-504 - octobre 2006 Retour au numéro
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