Stability of the Factor Structure of the Metabolic Syndrome across Pubertal Development: Confirmatory Factor Analyses of Three Alternative Models - 09/08/11
, Chaoyang Li, MD, PhD b, Yu-Kang Tu, PhD c, Earl Ford, MD, MPH b, Shumei S. Sun, PhD d, Terry T.-K. Huang, PhD, MPH e
Reprint requests: Elizabeth Goodman, MD, Pediatric Clinical Research Center, Floating Hospital for Children at Tufts Medical Center, 800 Washington Street, Box 854, Boston. MA 02111.Abstract |
Objective |
To test the fit and stability of 3 alternative models of the metabolic syndrome’s factor structure across 3 developmental stages.
Study design |
With data from the Fels Longitudinal Study, confirmatory factor analyses tested 3 alternative models of the factor structure underlying relationships among 8 metabolic syndrome-associated risks. Models tested were a 1-factor model (A), a 4-factor model (B), and a second-order latent factor model (C). Developmental stages assessed were prepuberty (ages 8-10), puberty (ages 11-15), and postpuberty (ages 16-20).
Results |
Convergence was achieved for all developmental stages for model A, but the fit was poor throughout (root mean square error of approximation > 0.1). Standardized factor loadings for waist circumference and body mass index were much stronger than those for fasting insulin at all 3 time points. Although prepuberty and postpuberty models converged for models B and C, each model had problems with Heywood cases. The puberty model did not converge for either model B or C.
Conclusions |
The hypothetical structures commonly used to support the metabolic syndrome concept do not provide adequate fit in a pediatric sample and may be variable by maturation stage. A components-based approach to cardiovascular risk reduction, with emphasis on obesity prevention and control, may be a more appropriate clinical strategy for children and youth than a syndromic approach.
Le texte complet de cet article est disponible en PDF.Mots-clés : BMI, CFA, DBP, EFA, HDL, MetS, RMSEA, SBP
Plan
| The contents of this paper do not necessarily represent the views of policies of the National Institutes of Health or the official position of the Centers for Disease Control and Prevention/the Agency for Toxic Substances and Disease Registry. |
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| Please see the Author Disclosure section at the end of this article. |
Vol 155 - N° 3
P. S5.e1-S5.e8 - septembre 2009 Retour au numéro
Article précédent
- Understanding the Nature of Metabolic Syndrome Components in Children and What They Can and Cannot Do to Predict Adult Disease
- Terry T.-K. Huang, Shumei S. Sun, Stephen R. Daniels
- Patterns of Change in Cardiometabolic Risk Factors Associated with the Metabolic Syndrome among Children and Adolescents: The Fels Longitudinal Study
- Chaoyang Li, Earl S. Ford, Terry T.-K. Huang, Shumei S. Sun, Elizabeth Goodman
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