Febrile Seizures and Cognitive Function in Young Adult Life: A Prevalence Study in Danish Conscripts - 09/08/11
, Vera Ehrenstein, MPH, DSc a, Barbara E. Mahon, MD, MPH b, c, Gunnar L. Nielsen, MD a, Kenneth J. Rothman, DrPH b, d, Henrik Toft Sørensen, MD, PhD, DMSc a, b
Reprint requests: Mette Nørgaard, Department of Clinical Epidemiology, Aarhus University Hospital, Sdr Skovvej 15, DK-9000 Aalborg, Denmark.Abstract |
Objective |
To examine the association between febrile seizures and cognitive performance in early adulthood.
Study design |
This is a population-based study using data linked from health-care databases and conscript records of Danish men born from 1977 to 1983. The association between febrile seizures and cognitive function, measured with the Boerge Prien validated group intelligence test, was examined overall and by age of seizure, adjusted for potential confounders. The analysis was restricted to men without a known history of epilepsy (n = 18 276).
Results |
Of the 18 276 eligible conscripts, 507 (2.8%) had a record of hospitalization with febrile seizures. Compared with conscripts with no such record, the adjusted prevalence ratio for having a Boerge Prien score in the bottom quartile was 1.08 (95% CI, 0.94-1.25). The adjusted prevalence ratios were 1.38 (95% CI, 1.07-1.79) for febrile seizures with an onset age of 3 months to <1 year, 0.98 (95% CI, 0.80-1.18) for febrile seizures with an onset age of 1 to 2 years, and 1.14 (95% CI, 0.79-1.66) for an onset age of 3 to 5 years.
Conclusions |
Overall, there was little association between febrile seizures and cognitive function.
Le texte complet de cet article est disponible en PDF.Mots-clés : BPP, ICD-8, ICD-10, PR, SGA, WAIS
Plan
| This study received financial support from the Western Danish Research Forum for Health Sciences and the Clinical Epidemiological Research Foundation. The authors declare no conflict of interest. |
Vol 155 - N° 3
P. 404-409 - septembre 2009 Retour au numéro
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