Death Receptors and Apoptosis - 09/08/11
Doi : 10.1016/j.det.2007.06.010
Emmanuel Contassot, PhD a, Olivier Gaide, MD, PhD b, Lars E. French, MD a, ⁎ 
a Department of Dermatology, Zurich University Hospital, Gloriastrasse 31, 8091 Zürich, Switzerland
b Departments of Pathology–Immunology and Dermatology, University Medical Center and University Hospital, Geneva, Switzerland
Corresponding author.Abstract |
Interactions between death receptors from the tumor necrosis factor superfamily and their ligands play a crucial role in the development and the integrity of the epidermis. The major consequence resulting from death receptor targeting is apoptosis. Evidence for dysregulation of death receptor signaling associated with the pathogenesis of selected cutaneous diseases, including toxic epidermal necrolysis, graft versus host disease, and skin cancer, are reviewed herein.
Le texte complet de cet article est disponible en PDF.Plan
© 2007
Elsevier Inc. Tous droits réservés.
Vol 25 - N° 4
P. 487-501 - octobre 2007 Retour au numéro
Article précédent
- Keratinocyte Growth Factor Receptors
- Vincenzo de Giorgi, Serena Sestini, Daniela Massi, Ilaria Ghersetich, Torello Lotti
- Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
- Christina Stefanaki, George P. Chrousos, Andreas Katsambas
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?