Glycemic Control in Youth with Diabetes: The SEARCH for Diabetes in Youth Study - 07/08/11

Doi : 10.1016/j.jpeds.2009.05.025

Diana B. Petitti, MD, MPH ^a, Georgeanna J. Klingensmith, MD ^b, Ronny A. Bell, PhD, MS ^c,^⁎ , Jeanette S. Andrews, MS ^d, Dana Dabelea, MD, PhD ^e, Giuseppina Imperatore, MD, PhD ^f, Santica Marcovina, PhD ^g, Catherine Pihoker, MD ^h, Debra Standiford, MSN, CNP ⁱ, Beth Waitzfelder, PhD ^j, Elizabeth Mayer-Davis, PhD ^k,^l
for the SEARCH for Diabetes in Youth Study Group
A complete list of the members of the SEARCH for Diabetes in Youth Study Group is available at www.jpeds.com (Appendix 1).
^a Biomedical Informatics, Arizona State University, Phoenix AZ
^b Pediatric Clinics, Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Denver, CO
^c Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC
^d Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC
^e Department of Epidemiology, Colorado School of Public Health, University of Colorado, Denver, CO
^f Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA
^g Department of Medicine, University of Washington, Seattle WA
^h Division of Endocrinology and Diabetes, Children’s Hospital and Regional Medical Center, Seattle WA
ⁱ Division of Endocrinology, Children’s Hospital Medical Center, Cincinnati OH
^j Pacific Health Research Institute, Honolulu HI
^k Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC
^l Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC

Reprint requests: Ronny Bell, PhD, PI, SEARCH Coordinating Center, Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1063.

Abstract

Objective

To assess correlates of glycemic control in a diverse population of children and youth with diabetes.

Study design

This was a cross-sectional analysis of data from a 6-center US study of diabetes in youth, including 3947 individuals with type 1 diabetes (T1D) and 552 with type 2 diabetes (T2D), using hemoglobin A_1c (HbA_1c) levels to assess glycemic control.

Results

HbA_1c levels reflecting poor glycemic control (HbA_1c ≥ 9.5%) were found in 17% of youth with T1D and in 27% of those with T2D. African-American, American Indian, Hispanic, and Asian/Pacific Islander youth with T1D were significantly more likely to have higher HbA_1c levels compared with non-Hispanic white youth (with respective rates for poor glycemic control of 36%, 52%, 27%, and 26% vs 12%). Similarly poor control in these 4 racial/ethnic groups was found in youth with T2D. Longer duration of diabetes was significantly associated with poorer glycemic control in youth with T1D and T2D.

Conclusions

The high percentage of US youth with HbA_1c levels above the target value and with poor glycemic control indicates an urgent need for effective treatment strategies to improve metabolic status in youth with diabetes.

Le texte complet de cet article est disponible en PDF.

Mots-clés : BMI, HbA1c, T1D, T2D

Plan

Funding and conflict of interest information available at www.jpeds.com (Appendix 2).

Export

Vol 155 - N° 5

P. 668 - novembre 2009 Retour au numéro

Article précédent

Higher Infant Blood Lead Levels with Longer Duration of Breastfeeding
Betsy Lozoff, Elias Jimenez, Abraham W. Wolf, Mary Lu Angelilli, Jigna Zatakia, Sandra W. Jacobson, Niko Kaciroti, Katy M. Clark, Min Tao, Marcela Castillo, Tomas Walter, Paulina Pino

| Article suivant

Early Life Origins of Low-Grade Inflammation and Atherosclerosis Risk in Children and Adolescents
Idoia Labayen, Francisco B. Ortega, Michael Sjöström, Jonatan R. Ruiz

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

Déjà abonné à cette revue ?

connectez-vous ou créez un compte

Glycemic Control in Youth with Diabetes: The SEARCH for Diabetes in Youth Study - 07/08/11

Abstract

Objective

Study design

Results

Conclusions

Plan

Export citations

Fichier

Contenu

Accès rapides

Mon compte

Aide & support

Plateformes Elsevier Masson

Déclaration CNIL