Neurobiology of Sleep - 05/08/11
Doi : 10.1016/j.ccm.2010.02.004
Brandon S. Lu, MD, MS a, ⁎ 
, Phyllis C. Zee, MD, PhD b
, Phyllis C. Zee, MD, PhD b a Department of Medicine, California Pacific Medical Center, 2351 Clay Street, Suite 501, San Francisco, CA 94115, USA
b Department of Neurology, Northwestern University, 710 North Lake Shore Drive, 11th Floor, Chicago, IL 60611, USA
Corresponding author.Résumé |
The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented.
Le texte complet de cet article est disponible en PDF.Keywords : Sleep neurobiology, Sleep regulation, Sleep-wake transition, Sleep disorders
Plan
| The authors have no financial conflict of interest with the subject discussed in this article. |
© 2010
Elsevier Inc. Tous droits réservés.
Vol 31 - N° 2
P. 309-318 - juin 2010 Retour au numéro
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