Aging with Muscular Dystrophy: Pathophysiology and Clinical Management - 05/08/11

Doi : 10.1016/j.pmr.2009.12.001

Gregory T. Carter, MD, MS ^a,^b,^⁎ , Michael D. Weiss, MD ^c, Joel R. Chamberlain, PhD ^c, Jay J. Han, MD ^d, Richard T. Abresch, MS ^d, Jordi Miró, PhD ^e, Mark P. Jensen, PhD ^a
^a Department of Rehabilitation Medicine, University of Washington School of Medicine, Box 356490, Seattle, WA 98195, USA
^b 1800 Cooks Hill Road, Suite East, Centralia, WA 98531, USA
^c Division of Neuromuscular Disorders, Department of Neurology, University of Washington School of Medicine, Box 356490, Seattle, WA 98195, USA
^d Department of Physical Medicine and Rehabilitation, University of California at Davis, Sacramento, CA 95817, USA
^e ALGOS, Research on pain, Rovira i Virgili University, Carretera de Valls s/n, 43007 Tarragona, Catalonia, Spain

Corresponding author. 1800 Cooks Hill Road, Suite East, Centralia, WA 98531.

Résumé

Major advances in the fields of medical science and physiology, molecular genetics, biomedical engineering, and computer science have provided individuals with muscular dystrophy (MD) with more functional equipment, allowing better strategies for improvement of quality of life. These advances have also allowed a significant number of these patients to live much longer. As progress continues to change management, it also changes patients’ expectations. A comprehensive medical and rehabilitative approach to management of aging MD patients can often fulfill expectations and help them enjoy an enhanced quality of life.

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Keywords : Muscular dystrophy, Aging, Pathophysiology, Management

Plan

This research was supported by the National Institutes of Health, National Institute of Child Health and Human Development, National Center for Rehabilitation Research (grant no. P01HD33988), and the National Institute for Disability Rehabilitation Research (grant no. H133B080024).