Optimal timing of periodontal disease treatment for prevention of adverse pregnancy outcomes: before or during pregnancy? - 03/08/11
, Pierre Buekens, MD, PhD a, Robert L. Goldenberg, MD b, Steven Offenbacher, DDS, PhD c, Xu Qian, MD, PhD d
Reprints: Xu Xiong, MD, DrPH, Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal St., SL-18, New Orleans, LA 70112-2715Résumé |
Several large randomized controlled clinical trials failed to find that standard periodontal therapy during pregnancy reduces the incidence of adverse pregnancy outcomes (eg, preterm birth and low birthweight). However, treating periodontal disease during pregnancy may be too late to reduce the inflammation that is related to the adverse pregnancy outcomes. Moreover, periodontal treatment during pregnancy can cause bacteremia, which itself may initiate the pathway leading to the adverse pregnancy outcomes. Finally, the periodontal treatments provided during pregnancy are not always effective in preventing the progression of periodontal disease during pregnancy. Pregnancy may not be an appropriate period for periodontal intervention(s). We hypothesize that periodontal treatment before pregnancy may reduce the rates of adverse pregnancy outcomes. Future randomized controlled trials are needed to test if treating periodontal disease in the prepregnancy period reduces the rate of adverse pregnancy outcomes.
Le texte complet de cet article est disponible en PDF.Key words : periodontal disease, prepregnancy periodontal treatment, preterm birth, randomized controlled clinical trial
| This article is part of a systematic review and metaanalysis of periodontal disease and birth outcomes that was supported by the Bill & Melinda Gates Foundation. |
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| Cite this article as: Xiong X, Buekens P, Goldenberg RL, et al. Optimal timing of periodontal disease treatment for prevention of adverse pregnancy outcomes: before or during pregnancy? Am J Obstet Gynecol 2011;205:111.e1-6. |
Vol 205 - N° 2
P. 111.e1-111.e6 - août 2011 Retour au numéro
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