Periprosthetic joint infection following Staphylococcus aureus bacteremia - 02/08/11
, Florian Banderet a, Peter Graber a, Werner Zimmerli a
Corresponding author. Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, CH-3010 Bern, Switzerland. Tel.: +41 31 632 32 99; fax: +41 31 632 49 66.Summary |
Objectives |
The incidence of haematogenous periprosthetic joint infections (PJI) among patients with remote infections has been reported to be less than 1%. This incidence may be much higher in cases after documented Staphylococcus aureus bacteremia (SAB). We evaluated the incidence of haematogenous PJI following SAB in patients with previously uninfected arthroplasties.
Methods |
A retrospective analysis of our cohort including patients with SAB and prosthetic joints at the Basel University Medical Clinic Liestal from 1998 to 2008.
Results |
We identified 31 patients with 45 uninfected prosthetic joints in situ at the time of SAB. In 12 patients (39%) and 13 arthroplasties (29%), SAB caused PJI. In comparison to nosocomial SAB, infections occurred only in cases with community-acquired SAB (p=0.002). PJI was diagnosed within a median time of 2.5 days (IQR 1–3.5) after admission. The comparison between patients with and without PJI revealed no significant difference in gender, age, comorbidities and number of prostheses per patient and age of the prosthesis.
Conclusions |
The rate of PJI after SAB is high, ranging from 30% to 40%, and clearly higher than rates reported for bacteremia with other pathogens. PJIs were observed in community-onset bacteremia, in which there is a typically delay from symptoms to antimicrobial treatment.
Le texte complet de cet article est disponible en PDF.Keywords : S. aureus bacteremia, Prosthetic joint infections, S. aureus
Plan
Vol 63 - N° 1
P. 17-22 - juillet 2011 Retour au numéro
Article précédent
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