Conservation of salivary function and new external head and neck radiation techniques - 10/12/10

Doi : 10.1016/j.anorl.2010.09.004

J. Thariat ^a,^⁎ , N. Guevara ^b, P.-Y. Marcy ^c, R.J. Bensadoun ^d, E. Bardet ^e, P. Giraud ^f
^a IBDC CNRS UMR 6543, département de radiothérapie oncologie, centre Antoine-Lacassagne, université Nice–Sophia-Antipolis, 33, avenue Valombrose, 06189 Nice cedex 2, France
^b Département de chirurgie ORL, institut universitaire de la tête et du cou, CHU, 33, avenue Valombrose, 06189 Nice cedex 2, France
^c Département de radiologie, centre Antoine-Lacassagne, université Nice–Sophia-Antipolis, 33, avenue Valombrose, 06189 Nice cedex 2, France
^d Service d’oncologie radiothérapique, CHU de Poitiers, BP 577, 86021Poitiers cedex, France
^e Département de radiothérapie oncologie, centre René-Gauducheau, site hospitalier Nord, boulevard Jacques-Monod, 44805 Nantes-Saint-Herblain cedex, France
^f Service d’oncologie radiothérapie, hôpital européen Georges-Pompidou, université Paris–Descartes, 20, rue Leblanc, 75015 Paris, France

Corresponding author.

Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.

pages	7
Iconographies	7
Vidéos	0
Autres	0

Summary

Introduction

New radiation therapy techniques seek to adapt dose distribution to three-dimensional tumor geometry, so as to deliver the lowest possible dose to normal tissue and at-risk organs. This is expected to enhance locoregional control and survival and to reduce complications and thereby improve quality of life. Post-radiation xerostomia significantly deteriorates quality of life.

Material and methods

New external radiation techniques (such as intensity-modulated conformal radiation therapy, RapidArc VMAT arc therapy, tomotherapy, CyberKnife^®, protontherapy, use of carbon ions) applicable in ENT are reviewed.

Results

Preliminary data show interesting results in terms of salivary function with highly conformal techniques.

Conclusion

In France, assessment is ongoing, financed under the Health Ministry’s “Support for Expensive Innovatory Techniques” scheme (STIC [Soutien aux techniques innovantes coûteuses]), as routine use is growing rapidly.

Le texte complet de cet article est disponible en PDF.

Keywords : Innovatory techniques, Intensity-modulated conformal radiation therapy, RapidArc VMAT arc therapy, Tomotherapy, CyberKnife^®, Protontherapy, Carbon ions, Xerostomia