A comparative STROBE analysis of 10-year oncologic results of SCPL-CHEP and endoscopic CO2 laser cordectomy for cT2N0M0 glottic squamous cell carcinoma - 25/04/25
Cet article a été publié dans un numéro de la revue, cliquez ici pour y accéder
Abstract |
Objective |
To compare 10-year oncologic results of supracricoid partial laryngectomy and cricohyoidoepiglottopexy (SCPL-CHEP) versus CO2 laser cordectomy (LC) for cT2N0M0 glottic squamous cell carcinoma (SCC).
Material and method |
Retrospective observational analysis of an inception cohort of 57 patients with isolated cT2N0M0 glottic SCC consecutively managed at a French university teaching otorhinolaryngology department during the years 1993–2013: 33 with SCPL-CHEP and 24 with LC. In all, 93% and 81% of patients were followed for respectively at least 5 years, or 10 years or until death. The main endpoint was 10-year actuarial overall and disease-free survival. Secondary endpoints comprised cause of death, 10-year actuarial local control, and 10-year laryngeal preservation estimates.
Results |
Ten-year survival was 58% whichever the surgical technique. Ten-year disease-free survival was 87% after SCPL-CHEP and 71% after LC (P=0.15). Death related to SCC occurred in 3 patients after LC but was not encountered after SCPL-CHEP. Ten-year local control differed: 100% after SCPL-CHEP versus 65% after LC, with 96% overall local control after salvage treatment. Ten-year laryngeal preservation differed: 97% after SCPL-CHEP versus 74% after LC (P=0.03).
Conclusions |
In patients with cT2N0M0 glottic SCC considered amenable to partial laryngeal surgery, the present long-term data should lead head and neck surgeons to discuss the benefits and pitfalls of both LC and SCPL-CHEP.
Le texte complet de cet article est disponible en PDF.Keywords : Glottic, T2 cancer, Partial laryngectomy, Supracricoid, Laser
Plan
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?