Central venous catheter-related deep vein thrombosis in severe inaugural diabetic ketoacidosis: A four case-report and literature review - 19/03/25
Abstract |
Introduction |
Type 1 diabetes (T1D), particularly diabetic ketoacidosis (DKA), is believed to induce a prothrombotic state, mainly due to activation of the coagulation system, platelets, and relative hypofibrinolysis.
Observations and discussion |
A central venous catheter (CVC) can be necessary in cases of severe inaugural DKA in the pediatric intensive care unit (PICU). Children with a CVC are at increased risk of thrombosis, particularly before the age of three.
Following a literature review and our experience in Toulouse (4 cases) of CVC-related thrombosis, we propose that CVC placement should be avoided as much as possible and alternative venous access should be preferred to minimize the risk of thrombosis.
Conclusion |
If CVC placement cannot be avoided, preventive anticoagulation should be considered, but further studies are needed to establish a proper protocol.
Le texte complet de cet article est disponible en PDF.Keywords : deep vein thrombosis, type 1 diabetes pediatric, T1D, central veinous catheter
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