Efficacy and safety of topical lignocaine anesthesia in improving patient satisfaction after endobronchial ultrasound–guided transbronchial needle aspiration under general anesthesia: A randomized controlled trial - 18/03/25
, Chao Liang a, c, ⁎ Abstract |
Background |
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is an effective technique used by thoracic surgeons and pulmonologists. This study evaluated the safety and efficacy of topical lignocaine anesthesia during bronchoscopy to improve the satisfaction of patients undergoing elective EBUS-TBNA under general anesthesia.
Methods |
This was a single-center prospective randomized, double-blind clinical trial in University-affiliated teaching hospitals. A total of 196 patients underwent elective EBUS-TBNA under general anesthesia. Patients were randomly assigned to receive topical anesthesia with 1% lignocaine (T) or saline (C). The primary outcome was coughing frequency immediately after laryngeal mask removal. Secondary outcomes included coughing frequency and intensity (visual analog scale [VAS]), vital sign changes, adverse events, postoperative pulmonary complications, and the Quality of Recovery-15 (QoR-15) questionnaire.
Results |
A total of 196 patients underwent randomization (91 in. T and 94 in C). Topical anesthesia with lignocaine significantly reduced the cough rate and VAS score immediately (P < 0.001 and < 0.001, respectively), 10 min (P < 0.001 and < 0.001), and 30 min (P = 0.005 and 0.001) after mask removal, and 2 h post-procedure (P = 0.003 and 0.006). No significant effect on vital signs was observed. The QoR-15 values 24 h after the procedure in group T were higher than those in group C (P < 0.001).
Conclusions |
During EBUS-TBNA under general anesthesia, 1% lignocaine for topical anesthesia significantly decreased the incidence of postoperative coughing and increased patient satisfaction. Topical anesthesia should be routinely administered to patients undergoing EBUS-TBNA under general anesthesia.
Registration |
Chinese Clinical Trial Registry; Registration number: ChiCTR2300072386; URL: showproj.html?proj=197032.
Le texte complet de cet article est disponible en PDF.Keywords : Topical anesthesia, Lignocaine, Endobronchial ultrasound-guided transbronchial needle aspiration, Coughing, Efficacy, Safety
Abbreviations : EBUS-TBNA, VAS, QoR-15, SpO2, NBP, LMA, HR, PPCs, BMI
Plan
Vol 44 - N° 2
Article 101495- avril 2025 Retour au numéro
Article précédent
- Effects of naloxegol on transit recovery in patients undergoing cardiac surgery: A randomized, double-blind, placebo-controlled trial
- Driss Laghlam, Hadrien Gibert, Messaouda Merzoug, Didier Leclerc, Lucas Coroyer, Philippe Estagnasie, Pierre Squara, Lee S. Nguyen, Guillaume Geri
- Improving paediatric undertriage in a regional trauma network — A registry cohort study
- François-Xavier Ageron, Jean-Noël Evain, Julie Chifflet, Cécile Vallot, Jules Grèze, Guillaume Mortamet, Pierre Bouzat, Tobias Gauss, For the TRENAU Group, François Albasini, Olivier Briot, Laurent Chaboud, Sophie Chateigner Coelsch, Alexandre Chaumat, Thomas Comlar, Olivier Debas, Guillaume Debaty, Emmanuelle Dupré-Nalet, Samuel Gay, Edouard Ginestie, Edouard Girard, Marc Haesevoets, Marie Hallain, Etienne Haller, Christophe Hoareau, Bernard Lanaspre, Safia Lespinasse, Romain Mermillod-Blondin, Philippe Nicoud, Thierry Roupioz, Damien Viglino, Jean-Marc Thouret, Pascal Usseglio-Polatera, Claire Vallenet, Bénédicte Zerr
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?