Cannabinoid Hyperemesis Syndrome Is Associated With High Disease Burden: An Internet-Based Survey - 20/02/25
, Callen Morrison, MD a, Aditya Loganathan, MD a, Soroush Shahamatdar, MD a, Alice Moon, BA a, Ryan Heidish, MD a, Michael Makutonin, MD a, Yan Ma, PhD b, Runjia Li, MS b, Ziva D. Cooper, PhD cAbstract |
Cannabinoid hyperemesis syndrome is an underrecognized condition associated with recurrent vomiting and abdominal pain in individuals with prolonged cannabis use. This study used an internet-based survey targeting individuals with self-reported cannabinoid hyperemesis syndrome to assess the burden of disease and to examine associations between heavy cannabis use, early initiation of cannabis use, and cannabinoid hyperemesis syndrome episode frequency. A total of 1,052 participants were included, with the majority reporting frequent cannabis use and significant health care utilization, including emergency department visits and hospitalizations. This study highlights the substantial disease burden associated with cannabinoid hyperemesis syndrome in an online support group cohort and underscores the possible risks of heavy daily cannabis use and of use starting in adolescence. Future studies on heavy cannabis users are necessary to further elucidate cannabinoid hyperemesis syndrome and its link to daily cannabis use and the dangers of heavy use in adolescence.
Le texte complet de cet article est disponible en PDF.Keywords : Cannabis, Cannabinoid, Hyperemesis, Syndrome
Plan
| Supervising editor: Andrew A. Monte, MD. Specific detailed information about possible conflict of interest for individual editors is available at editors. |
|
| Author contributions: ACM conceptualized the study and supervised the project. CM, AL, SS, AM, and RH contributed to data collection, analysis, and manuscript drafting. YM and RL performed the statistical analysis and provided methodological expertise. ZDC contributed to the interpretation of findings and revision of the manuscript for critical content. All authors reviewed and approved the final manuscript. ACM takes responsibility for the manuscript as a whole. |
|
| Data sharing statement: Data from this study are available on reasonable request. For access to the data set, please contact the corresponding author at ameltzer@mfa.gwu.edu. |
|
| All authors attest to meeting the four ICMJE.org authorship criteria: (1) Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND (2) Drafting the work or revising it critically for important intellectual content; AND (3) Final approval of the version to be published; AND (4) Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. |
|
| Funding and support: By Annals’ policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org/). The authors have stated that no such relationships exist. |
|
| Please see page XX for the Editor’s Capsule Summary of this article. |
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?