Macropolycytes as a sepsis biomarker - 19/02/25
Doi : 10.1016/j.morpho.2024.100923
M.P. Barros Pinto a, b, ⁎ 
a Hospital Santa Maria, Centro Hospitalar Universitário Lisboa Norte, EPE, Lisbon, Portugal
b Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
⁎Correspondence. Centro Hospitalar Universitário Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-028 Lisboa, Portugal.Centro Hospitalar Universitário Lisboa Norte, EPEAv. Prof. Egas MonizLisboa1649-028Portugal
Highlights |
• | Analyzers can erroneously count macropolycytes as monocytes. |
• | When a high monocytes count is obtained by the analyzers, a peripheral blood film should be performed to confirm this assessment. |
• | The identification of macropolycytes can play an important role as a sepsis biomarker. |
Summary |
A 16-year-old male patient who underwent a kidney transplant developed a septic shock. A full blood count (FBC) was performed and the presence of monocytosis in the automatic FBC, the overlap between neutrophils and monocytes in the WBC scatter plot, and a “MO blast” flag triggered by the analyzer, led to a peripheral blood film (PBF). PBF revealed the presence of macropolycytes that were erroneously count as monocytes by the analyzer. Macropolycytes can play an important role as a sepsis biomarker.
Le texte complet de cet article est disponible en PDF.Keywords : Macropolycytes, MDW, Sepsis
Plan
© 2024
The Author(s). Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 109 - N° 364
Article 100923- mars 2025 Retour au numéro
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