Symposia — Conferences — Oral Communications - 21/11/24

Doi : 10.14283/jfa.2021.34

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Plan

Symposia

S1- PRELIMINARY RESULTS OF THE SPRINTT PROJECT.. Francesco Landi (Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome Italy):

S2- IMPROVING CARE FOR OLDER ADULTS LIVING WITH FRAILTY: RESULTS FROM THE CANADIAN FRAILTY NETWORK'S TRANSFORMATIVE GRANT STUDIES.. John Muscedere (Scientific Director and CEO, Canadian Frailty Network; Department of Critical Care Medicine, Queen's University, Canada):

S3- RESILIENCE AND MULTIFACTORIAL STRESSORS AMONG OLDER ADULTS DURING THE COVID-19 PANDEMIC.. Karen Bandeen-Roche (Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA):

S4- WHO ICOPE IMPLEMENTATION PILOT PROGRAMME. Yuka Sumi¹, Bruno Vellas²(1. World Health Organization, Geneva, Switzerland; 2. WHO Toulouse Collaborative Center, Toulouse, France)

S5- FRAILTY IN RHEUMATIC DISEASES: EVIDENCE TO DATE AND LESSONS LEARNED. Devyani Misra (Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard Medical School, Boston, MA, USA)

S6- FRAILTY AND SARCOPENIA IN LONG COVID-19. Riccardo Calvani, Emanuele Marzetti (Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy)

S7- TOWARD MICROWAVE-BASED ASSESSMENT FOR DIAGNOSIS AND MANAGEMENT OF SARCOPENIA. Taco J. Blokhuis (Maastricht University Medical Center, Traumatology Department, Maastricht, The Netherlands)

S9- COVID-19 & DECONDITIONING IN OLDER ADULTS: EXERCISE AS SOLUTION FROM CLINIC TO COMMUNITY SETTING. Mylene Aubertin-Leheudre (Université du Québec à Montréal/ Université de Liège, Montréal, Québec, Canada)

Oral Communications

OC1- CLINICAL TRIAL OF METFORMIN FOR FRAILTY PREVENTION IN COMMUNITY-DWELLING OLDER ADULTS WITH PRE-DIABETES. Sara Espinoza, Nicolas Musi, Chen-pin Wang, Joel Michalek, Beverly Orsak, Alicia Conde, Amir Tavabi, Daniel MacCarthy, Qianqian Liu, Tiffany Cortes (Departments of Medicine and Population Health Sciences, Sam & Ann Barshop Institute for Longevity & Aging Studies, University of Texas Health Science Center, San Antonio, Texas, Geriatrics Research, Education & Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas)

OC2- IMPACT OF L-CITRULLINE SUPPLEMENTATION COMBINED WITH LOW-INTENSITY RESISTANCE TRAINING ON BODY COMPOSITION AND STRENGTH IN POSTMENOPAUSAL WOMEN. Arturo Figueroa, Arun Maharaj, Stephen M. Fischer (Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, TX, USA)

OC3- DOES KRILL OIL SUPPLEMENTATION RESULT IN AN INCREASE IN MUSCLE FUNCTION? A RANDOMISED CONTROLLED TRIAL. Saleh AA Alkhedhairi, AM Hunter, E Combet, TJ Quinn, SR Gray (Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK; Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Saudi Arabia; School of Human Sciences, University of Western Australia, Perth, Australia; Faculty of Health Sciences and Sport, University of Stirling, Stirling, Scotland)

OC4- THE HOLISTIC ASSESSMENT AND CARE PLANNING IN PARTNERSHIP STUDY (HAPPI): RESULTS OF A FEASIBILITY RANDOMIZED CONTROLLED TRIAL OF A NURSE-LED INTERVENTION FOR COMMUNITY-DWELLING OLDER PEOPLE WHO LIVE WITH FRAILTY. Helen Lyndon, Jos M. Latour, Jonathan Marsden, Bridie Kent (University of Plymouth, United Kingdom)

OC6- SARCOPENIA AND ADHERENCE AFFECT RESPONSE TO AN EXERCISE/NUTRITION INTERVENTION IN NURSING HOME RESIDENTS. Emelie Karlsson¹, Helena Grönstedt², Gerd Faxén-Irving³, Erika Franzén⁴, Yvette Luiking⁵, Ake Seiger³, Sofia Vikström⁶, Anders Wimo⁷, Tommy Cederholm⁸, Anne-Marie Boström⁹(1. Dept. of Clinical Science and Education, Karolinska Institutet (KI), Stockholm, Sweden; 2. Allied Health Professionals, Function Area Occupational Therapy and Physiotherapy, Karolinska University Hospital, Stockholm, Sweden; 3. Dept. of Neurobiology, Care Science and Society, Division of Clinical Geriatrics, KI, Stockholm, Sweden; 4. Dept. of Neurobiology, Care Science and Society, Division of Physiotherapy, KI, Stockholm, Sweden; 5. Danone Nutricia Research, Utrecht, the Netherlands; 6. Dept. of Neurobiology, Care Science and Society, Division of Occupational Therapy, KI, Stockholm, Sweden; 7. Dept. of Neurobiology, Care Science and Society, Division of Neurogeriatrics, KI, Stockholm, Sweden; 8. Dept. of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden; 9. Dept. of Neurobiology, Care Science and Society, Division of Nursing, KI, Stockholm, Sweden)

OC7- UROLITHIN A SUPPLEMENTATION IMPROVES MUSCLE STRENGTH IN HUMANS AND POSITIVELY IMPACTS BIOMARKERS OF CELLULAR HEALTH. Anurag Singh¹, Davide D'Amico¹, Pénélope A. Andreux¹, Andéané M. Fouassier¹, William Blanco-Bose¹, Johan Auwerx², Chris Rinsch¹(1. Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland; 2. Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland)

OC8- THE COMBINED EFFECTS OF PHYSICAL FRAILTY AND COGNITIVE IMPAIRMENT ON ALL-CAUSE AND EMERGENCY DEPARTMENT-RELATED HOSPITALIZATIONS: RESULTS FROM LINKED COHORT AND CLAIMS DATA. Brian Buta¹, Shang-En Chung¹, Orla C. Sheehan^1,2, Marcela D. Blinka¹, Susan Gearhart¹, Qian-Li Xue¹(1. Johns Hopkins University, Baltimore, MD, USA; 2. Connolly Hospital Blanchardstown, Dublin, Ireland)

OC9- THE EFFECTS OF VITAMIN D SUPPLEMENTATION ON FRAILTY IN COMMUNITY-DWELLING OLDER ADULTS AT RISK FOR FALLS. Yurun Cai¹, Amal A. Wanigatunga^1,2, Christine M. Mitchell^1,3, Jacek K. Urbanek^2,4, Edgar R. Miller III^3,5, Stephen P. Juraschek⁶, Erin D. Michos^3,7, David L. Roth^2,4, Lawrence J. Appel^1,3,5, Jennifer A. Schrack^1,2(1. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; 2. Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA; 3. Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University and Medical Institutions, Baltimore, Maryland, USA; 4. Division of Geriatric Medicine and Gerontology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 5. Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 6. Division of General Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School Teaching Hospital, Boston, Massachusetts, USA; 7. Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA)

OC10- PRO-AUTOPHAGIC AND ANABOLIC AMINO ACIDS IMPROVE MUSCLE FORCE DURING AGING. Claire Boutry-Regard, Gabriele Civiletto, Philipp Gut, Jérôme N. Feige (Nestlé Research, EPFL Innovation Park, Lausanne, Switzerland)

OC11- MYOGENIC AND STRESS FACTORS ARE DIFFERENTIALLY EXPRESSED IN SKELETAL MUSCLE OF OLDER ADULTS WITH LOW MUSCLE STRENGTH. Sebastiaan Dalle¹, Jolan Dupont², Lenore Dedeyne³, Evelien Gielen³, Katrien Koppo¹(1. Exercise Physiology Research Group, Dept. of Movement Sciences, KU Leuven, Belgium; 2. Geriatrics and Gerontology, Department of Public Health and Primary Care, KU Leuven & Department of Geriatric Medicine, UZ Leuven, Belgium; 3. Geriatrics and Gerontology, Department of Public Health and Primary Care, KU Leuven, Belgium)

OC12- THE EFFECT OF YOUNG AND OLD EX VIVO HUMAN SERUM ON CELLULAR PROTEIN SYNTHESIS AND GROWTH IN AN IN VITRO MODEL OF AGEING. Sophie L. Allen^1,2, Ryan N. Marshall^1,3, Sophie J. Edwards¹, Janet M. Lord^2,3,4, Gareth G. Lavery^2,3,5,6, Leigh Breen^1,2,3(1. School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, UK; 2. National Institute for Health Research, Birmingham Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK; 3. MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, University of Birmingham, UK; 4. Institute of Inflammation and Ageing, University of Birmingham, UK; 5. Institute of Metabolism and Systems Research, University of Birmingham, UK; 6. Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partner, Birmingham, UK)

OC13- EPIGENETIC AGE ACCELERATION AND CHANGE IN FRAILTY IN MOBILIZE BOSTON. Benjamin Seligman^1,2,4, Sarah D. Berry^1,3,4, Lewis I. Lipsitz^1,3,4, Douglas P. Kiel^1,3,4(1. Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2. New England Geriatrics Research, Education, and Clinical Center, Veterans Affairs Boston Health Care System, Boston, MA, USA; 3. Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA; 4. Harvard Medical School, Boston, MA, USA)

OC14- SEX DIFFERENCES IN MUSCLE-AGEING: A CROSS-SECTIONAL STUDY. Jelle CBC de Jong^1,2, Brecht J Attema¹, Arie G Nieuwenhuizen¹, Lars Verschuren³, Martien PM Caspers³, Marjanne D Van der Hoek^1,4,5, Feike R Van der Leij^4,6, Robert Kleemann², Anita M van den Hoek², Jaap Keijer¹(1. Human and Animal Physiology, Wageningen University, Wageningen, the Netherlands; 2. Department of Metabolic Health Research, The Netherlands Organization for Applied Scientific Research (TNO), Leiden, the Netherlands; 3. Department of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), Zeist, the Netherlands; 4. Applied Research Centre Food and Dairy, van Hall Larenstein University of Applied Scineces, Leeuwwarden, the Netherlands; 5. MCL Academy, Medical Centre Leeuwarden, Leeuwarden, the Netherlands; 6. RIC-AFL Inholland University of Applied Sciences, Delft and Amsterdam, the Netherlands)

OC15- ADVERSE MUSCLE COMPOSITION PREDICTS ALL-CAUSE MORTALITY IN THE UK BIOBANK IMAGING STUDY. J. Linge^1,2, M. Petersson¹, M.F. Forsgren^1,2,3, A.J. Sanyal⁴, O. Dahlqvist Leinhard^1,2,3(1. AMRA Medical, Linköping, Sweden; 2. Department of Health, Medicine and Caring Sciences, Linköping University, Sweden; 3. Center for Medical Image Science and Visualization (CMIV), Linköping University, Sweden; 4. Department of Internal Medicine and Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA)

OC16- SARCOPENIA AND SARCOPENIC OBESITY AND INCIDENT FALL RISK: DATA FROM THE NATIONAL HEALTH AND AGING TRENDS SURVEY. John A. Batsis^1,2, Christian Haudenschild³, Rebecca S. Crow^4,5, Meredith Gilliam¹, Todd A. Mackenzie^5,6(1. Division of Geriatric Medicine and Center for Aging and Health, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 2. Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 3. University of Minnesota, Minneapolis, Minnesota, USA; 4. Section of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA; 5. Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA; 6. Department of Biomedical Data Science, Dartmouth College, Hanover, New Hampshire, USA)

OC17- SELF-MANAGEMENT BEHAVIOUR AND THE FLUCTUATIONS OF FRAILTY AMONG COMMUNITY-DWELLING OLDER ADULTS IN TAIWAN: A NATIONAL LONGITUDINAL POPULATION BASED COHORT STUDY. Thi Lien To¹, Ching-Pyng Kuo², Chih-Jung Yeh³, Wen-Chun Liao⁴, Meng-Chih Lee⁵(1. Graduate Institute of Public Health, China Medical University, Taichung, Taiwan; 2. School of Nursing, Chung Shan Medical University, Taichung, Taiwan; 3. School of Public Health, Chung Shan Medical University, Taichung, Taiwan; 4. School of Nursing, China Medical University, Taichung, Taiwan; 5. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan)

OC18- A RANDOMIZED CONTROLLED TRIAL IS TO ASSESS WHETHER PHYSICAL ACTIVITY AND/OR NUTRITION INTERVENTION REDUCE FRAILTY IN PRE-FRAIL OLDER PEOPLE: STAYING UPRIGHT AND EATING WELL RESEARCH, SUPER STUDY. Ruth Teh¹, Daniel Barnett², Ngaire Kerse¹, Debra Waters³, Leigh Hale⁴, Anna Rolleston⁵, Richard Edlin⁶, Eve Leilua¹, Esther Tay¹, Avinesh Pillai²(1. Department of General Practice and Primary Health Care, School of Population Health, University of Auckland, Auckland, New Zealand; 2. Department of Statistics, Faculty of Science, University of Auckland, Auckland, New Zealand; 3. Department of Medicine, School of Physiotherapy, University of Otago, Dunedin, New Zealand; 4. Centre for Health, Activity and Rehabilitation Research, School of Physiotherapy, University of Otago, Dunedin, New Zealand; 5. The Centre of Health, Tauranga, New Zealand; 6. Health Systems Group, School of Population Health, University of Auckland, Auckland, New Zealand)

OC19- FRAILTY TRAJECTORIES IN THREE LONGITUDINAL STUDIES OF AGING: IS THE LEVEL OR THE RATE OF CHANGE MORE PREDICTIVE OF MORTALITY? Ge Bai¹, Agnieszka Szwajda¹, Yunzhang Wang¹, Xia Li¹, Hannah Bower², Ida Karlsson^1,3, Boo Johansson⁴, Anna K. Dahl Aslan^1,5, Nancy L. Pedersen¹, Sara Hägg¹, Juulia Jylhävä¹(1. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2. Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm; 3. Institute of Gerontology and Aging Research Network–Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden; 4. Department of Psychology & Centre for Ageing and Health (AgeCap), University of Gothenburg, Gothenburg, Sweden; 5. School of Health Sciences, University of Skövde, Skövde, Sweden)

OC20- ACCELEROMETER-DERIVED AGE- AND SEX-SPECIFIC PHYSICAL ACTIVITY INTENSITY METRICS: PREDICTIVE VALIDITY FOR ALL-CAUSE MORTALITY. J.H. Migueles¹, C. Cadenas-Sanchez², E.J. Shiroma³(1. Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; 2. Institute for Innovation and Sustainable Development in the Food Chain (IS-FOOD), Public University of Navarra, Pamplona, Spain; 3. Laboratory of Epidemiology and Population Science, National Institute on Aging, Baltimore, Maryland, USA)

OC21- CAN JUMP TEST PERFORMANCE BE USED AS A SCREENING TOOL TO PREDICT THE HIP SKELETAL STATUS IN OLDER ADULTS? Harshvardhan Singh¹, Zhaojing Chen², Samuel Buchanan³, Michael G. Bemben⁴, Debra A. Bemben⁴(1. University of Alabama at Birmingham, USA; 2. California State University San Bernardino, USA; 3. University of Texas Rio Grande Valley, USA; 4. University of Oklahoma, USA)

OC22- INFLAMMATORY MARKERS ARE ASSOCIATED WITH QUALITY OF LIFE, PHYSICAL ACTIVITY & GAIT SPEED BUT NOT SARCOPENIA IN AGED MEN (40-79Y). Jolan Dupont^1,2, Leen Antonio³, Lenore Dedeyne¹, Terence W. O'Neill⁴, Dirk Vanderschueren³, Jos Tournoy^1,2, Katrien Koppo⁵, Evelien Gielen^1,2(1. Geriatrics & Gerontology, Department of Public Health and Primary Care, KU Leuven, Belgium; 2. Department of Geriatric medicine, UZ Leuven, Belgium; 3. Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Belgium; 4. Arthritis Research UK Centre for Epidemiology & NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, UK; 5. Exercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Belgium)

OC23- SKIN AUTOFLUORESENCE, A NON-INVASIVE BIOMARKER OF ADVANCED GLYCATION END-PRODUCTS (AGES), IS ASSOCIATED WITH FRAILTY: THE ROTTERDAM STUDY. Komal Waqas¹, Jinluan Chen¹, Katerina Trajanoska^1,2, M. Arfan Ikram², André G. Uitterlinden^1,2, Fernando Rivadeneira¹, T. Voortman², M. Carola Zillikens¹(1. Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands; 2. Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands)

OC24- THE HIGH INTENSITY INTERVAL TRAINING AND CITRULLINE SUPPLEMENTATION ALTER THE CIRCULATING AND MUSCLE MICRORNA LEVELS IN OBESE ADULTS OVER 60 YEARS: A VALIDATION STUDY. Marjorie Millet¹, Martine Croset¹, Elisabeth Sornay-Rendu¹, Philippe Noirez^2,3, José Morais⁴, Mylène Aubertin-Leheudre³, Jean-Charles Rousseau¹, Roland Chapurlat^1,5,6(1. INSERM 1033, Lyon, France; 2. UFR des Sciences et Techniques des Activités Physiques et Sportives de Paris, Université Paris-Descartes, Paris, France; 3. Département des Sciences de l'Activité Physique, Université du Québec à Montréal, Montréal, Québec, Canada; 4. Faculté de Médecine, Département de Gériatrie, Université McGill, Montréal, Québec, Canada; 5. Hôpital E. Herriot, Hospices Civils de Lyon, Lyon, France; 6. Université de Lyon, Lyon, France)

OC25- FRAILTY IS ASSOCIATED WITH A HIGHER MORTALITY IN OLDER PEOPLE WITH CANCER HISTORY: EVIDENCE FROM THE 1999–2014 NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY. Dongyu Zhang¹, Erin Mobley², Todd Manini³, Christiaan Leeuwenburgh³, Stephen Anton³, Caretia Washington⁴, Daohong Zhou⁵, Alexander Parker⁶, Paul Okunieff⁷, Marco Pahor³, Dejana Braithwaite^1,3,8(1. Department of Epidemiology, University of Florida College of Public Health and Health Professions, Gainesville, FL, USA; 2. Department of Surgery, University of Florida College of Medicine, Jacksonville, FL, USA; 3. Department of Aging & Geriatric Research, University of Florida College of Medicine, Gainesville, FL, USA; 4. University of Florida College of Medicine, Gainesville, FL, USA; 5. Department of Pharmacodynamics, University of Florida College of Pharmacy, Gainesville, FL, USA; 6. University of Florida College of Medicine, Jacksonville, FL, USA; 7. Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA; 8. University of Florida Health Cancer Center, Gainesville, FL, USA)

OC26- PLASMA PROTEOMIC PROFILE OF FRAILTY INDEX TRAJECTORIES IN THE INCHIANTI STUDY. Toshiko Tanaka¹, Stefania Bandinelli², Luigi Ferrucci¹(1. Longitudinal study section, National Institute on Aging, Baltimore; 2. Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy)

OC28- ONSET OF FRAILTY AND DIABETES IN OLDER U.S. VETERANS. Tiffany M. Cortes^1,2,3, Daniel MacCarthy⁴, Chen-Pin Wang^2,3,4, Nicolas Musi^1,2,3, Sara E. Espinoza^1,2,3(1. Department of Medicine, UT Health San Antonio, Texas, USA; 2. Barshop Institute for Longevity & Aging Studies, UT Health San Antonio, Texas, USA; 3. Geriatrics Research, Education and Clinical Center, South Texas Veterans Health System, USA; 4. Department of Epidemiology and Biostatistics UT Health San Antonio, Texas, USA)

OC29- REPLACING UNINTENTIONAL WEIGHT LOSS WITH SARCOPENIA IN PHYSICAL FRAILTY PHENOTYPE CONSTRUCT FOR CLINICAL USE. Xiaomeng Chen¹, Omid Shafaat^1,2, Yi Liu¹, Nadia M. Chu^1,3, Cliff Weiss², Dorry L. Segev^1,3, Mara McAdams-DeMarco^1,3(1. Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA; 2. Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, MD, USA; 3. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA)

OC30- FRAILTY IN SYSTEMIC LUPUS ERYTHEMATOSUS: AN ADMINISTRATIVE CLAIMS DATA ANALYSIS. Sarah B. Lieber^1,2, Iris Navarro-Millan^1,2, Musarrat Nahid², Mangala Rajan², Sebastian E. Sattui¹, Lisa A. Mandl^1,2(1. Hospital for Special Surgery, New York, NY, USA; 2. Weill Cornell Medicine, New York, NY, USA)

OC31- DOES ALTERED LIPID METABOLISM DUE TO LOSS OF SREBF1 DECREASE MUSCLE MASS IN ZEBRAFISH? Rajashekar Donaka, Chen Shochat, David Karasik (The Azrieli Faculty of Medicine, Bar-IIan University, Safed, Israel)

OC32- PHYSICAL FRAILTY TRAJECTORIES IN OLDER U.S. NURSING HOME RESIDENTS. Yiyang Yuan^1,2, Kate L. Lapane², Jennifer Tjia², Jonggyu Baek², Shao-Hsien Liu², Christine M. Ulbricht³(1. Clinical and Population Health Research PhD Program, Graduate School of Biomedical Sciences, University of Massachusetts Medical School, Worcester, MA, USA; 2. Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA; 3. National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA)

OC33- ADVERSE MUSCLE COMPOSITION PREDICTS ALL-CAUSE MORTALITY INDEPENDENT OF FUNCTIONAL PERFORMANCE LEVEL IN THE UK BIOBANK IMAGING STUDY. J. Linge^1,2, M. Petersson¹, M.F. Forsgren^1,2,3, A.J. Sanyal⁴, O. Dahlqvist Leinhard^1,2,3(1. AMRA Medical, Linköping, Sweden; 2. Department of Health, Medicine and Caring Sciences, Linköping University, Sweden; 3. Center for Medical Image Science and Visualization (CMIV), Linköping University, Sweden; 4. Department of Internal Medicine and Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA)

OC34- A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY IN JAPAN TO INVESTIGATE THE SAFETY AND EFFICACY OF LOMECEL-B ADMINISTRATION BY LONGEVERON IN PATIENTS WITH AGING FRAILTY: STUDY DESIGN AND RATIONALE. Kevin N. Ramdas, Keyvan Yousefi, Geoff Green, Lisa Moss, Ben Hitchinson, Liliana Diaz, Jessica Protenic, Joshua M. Hare, Anthony A. Oliva, Jr. (Longeveron Inc., Miami, USA)

OC35- LOWER-EXTREMITY FUNCTION PREDICTS FRAILTY THROUGH ACTIVE LEISURE ACTIVITIES: A LONGITUDINAL MEDIATION ANALYSIS. Meng Zhao, Yaqi Wang, Shan Wang, Yuan Yang, Ming Li, Kefang Wang (School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China)

OC36- DIFFERENCES IN INTRINSIC CAPACITY AND BIOLOGICAL PROFILE ACCORDING TO LONGITUDINAL FRAILTY TRAJECTORIES IN COMMUNITY-DWELLING OLDER ADULTS. Emmanuel Gonzalez Bautista^1,2, Wan-Hsuan Lu^1,2, Bruno Vellas^1,2, Philipe de Souto Barreto^1,2(1. Gerontopole of Toulouse, Institute of Ageing, Toulouse University Hospital (CHU Toulouse), Toulouse, France; 2. Inserm CERPOP — UMR1295, University of Toulouse III, Toulouse, France)

OC38- LOWER URINARY TRACT SYMPTOMS AND INCIDENT FUNCTIONAL LIMITATIONS IN OLDER COMMUNITY-DWELLING MEN. Scott R. Bauer^1,2,3, Peggy M. Cawthon^4,5, Kristine E. Ensrud^6,7, Anne M. Suskind², John C. Newman^8,9, Howard A. Fink^6,7, Kaiwei Lu³, Rebecca Scherzer^1,3, Kenneth Covinsky^3,9, Lynn M. Marshall^10,11 for the Osteoporotic Fractures in Men (MrOS) Research Group (1. Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA, YSA; 2. Department of Urology, University of California, San Francisco, CA, USA; 3. San Francisco VA Medical Center, San Francisco, CA, USA; 4. Research Institute, California Pacific Medical Center, San Francisco, CA, USA; 5. Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA; 6. Department of Medicine and Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA; 7. Veterans Affairs Health Care System, Minneapolis, MN, USA; 8. Buck Institute for Research on Aging, Novato, CA, USA; 9. Division of Geriatrics, Department of Medicine, University of California, San Francisco, CA, USA; 10. Oregon Health and Science University-Portland State University School of Public Health, Portland OR, USA; 11. Department of Orthopaedics and Rehabilitation, Oregon Health and Science University, Portland, OR, USA)

OC39- ADHERENCE TO A MEDITERRANEAN LIFESTYLE AND FRAILTY OCCURRENCE IN OLDER ADULTS: THE SENIORS-ENRICA-1 COHORT. Javier Maroto-Rodriguez¹, Mario Delgado-Velandia¹, Rosario Ortola¹, Esther Garcia-Esquinas¹, David Martinez-Gomez^1,2, Ellen Struijk¹ Esther Lopez-Garcia^1,2, Fernando Rodriguez-Artalejo^1,2, Mercedes Sotos-Prieto¹(1. Universidad Autonoma de Madrid-IdiPaz and CIBERESP, Spain; 2. IMDEA Food Institute, Spain)

OC40- THE FIRST ICOPE REMOTE MONITORING PLATFORM IN THE OCCITANIA REGION (FRANCE): ORGANIZATION AND FUNCTIONING. Neda Tavassoli, Caroline Berbon, Justine De Kerimel, Celine Mathieu, Christine Lafont, Catherine Takeda, Magali Poly, Sandrine Augusto, Laure Bouchon, Florence Da Costa, Melanie Comte, Maria Soto, Bruno Vellas (Gérontopôle, Centre Hospitalo-Universitaire de Toulouse, équipe Régionale Vieillissement et Prévention de la Dépendance (ERVPD), Hôpital La Grave, Place Lange, TSA 60033, Toulouse, France)

OC41- SEX-SPECIFIC ASSOCIATION OF SOCIAL FRAILTY WITH INTRINSIC CAPACITY IN COMMUNITY-DWELLING OLDER ADULTS. Chi Hsien Huang^1,2,3, Kiwako Okada⁴, Eiji Matsushita⁴, Chiharu Uno^4,9, ShosukeSatake^5,6, Beatriz Arakawa Martins^1,7,8, Masafumi Kuzuya^1,9(1. Department of Community Health and Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan; 2. Department of Family Medicine, E-Da Hospital, Kaohsiung City, Taiwan; 3. School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung City, Taiwan; 4. Graduate School of Nutritional Sciences, Nagoya University of Arts and Sciences, Aichi Prefecture, Japan; 5. Section of Frailty Prevention, Department of Frailty Research, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 6. Department of Geriatric Medicine, Hospital, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 7. Adelaide Geriatrics Training and Research with Aged Care (G-TRAC Centre), Discipline of Medicine, Adelaide Medical School, University of Adelaide, South Australia, Australia; 8. National Health and Medical Research Council Centre of Research Excellence in Frailty and Healthy Ageing, University of Adelaide, South Australia, Australia; 9. Institutes of Innovation for Future Society, Nagoya University, Aichi Prefecture, Japane)

OC42- AGE-SPECIFIC DIFFERENCES IN ANTHROPOMETRIC, MOTOR AND NEUROPSYCHOLOGICAL FACTORS IN GRIP STRENGTH. David Russ¹, Nathan Wages², Leatha Clark², Julie Suhr³, Brian Clark²(1. School of Physical Therapy and Rehabilitation Sciences, University of South Florida, Tampa, FL, USA; 2. Ohio Musculoskeletal Neurological Institute, Athens, OH, USA; 3. Department of Psychology, Ohio University, Athens, OH, USA)

OC43- EFFECTS OF PREOPERATIVE FRAILTY ON OUTCOMES FOLLOWING SURGERY AMONG PATIENTS WITH GASTROINTESTINAL TUMORS: A SYSTEMATIC REVIEW AND META-ANALYSIS. Lingyu Ding¹, Jinling¹, Hanfei Zhu¹, Shuqin Zhu¹, Xinyi Xu², Qin Xu¹(1. School of Nursing, Nanjing Medical University, Nanjing, China; 2. Faculty of Health, Queensland University of Technology, Brisbane, Australia)

OC44- ASSOCIATION OF EXECUTIVE FUNCTION AND POSTURAL STABILITY IN COMMUNITY-DWELLING OLDER ADULTS: A LONGITUDINAL APPROACH. Jennifer Blackwood¹, Reza Amini², Gerry Conti³, Quinn Hanses³, Rebekah Taylor³, Rachelle Naimi³, Deena Fayyad⁴(1. Department of Physical Therapy at the University of Michigan-Flint, USA; 2. Department of Public Health and Health Sciences at the University of Michigan-Flint, USA; 3. Department of Occupational Therapy at the University of Michigan-Flint, USA; 4. Department of Psychology at the University of Michigan)

OC45- SIMPLE CARBOHYDRATE INTAKE AND HIGHER RISK FOR PHYSICAL FRAILTY OVER 15 YEARS IN COMMUNITY-DWELLING OLDER ADULTS. Virginie Chuy^1,2, Mélissa Gentreau³, Sylvaine Artero³, Claire Berticat⁴, Vincent Rigalleau^1,5, Karine Pérés¹, Catherine Helmer^1,6, Cécilia Samieri¹, Catherine Féart¹(1. Univ. Bordeaux, INSERM, BPH, U1219, Bordeaux, France; 2. Univ. Bordeaux, CHU Bordeaux, Department of Dentistry and Oral Health, France; 3. Institute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France; 4. ISEM, University of Montpellier, CNRS, EPHE, IRD, Montpellier, France; 5. Univ. Bordeaux, CHU Bordeaux, Department of Endocrinology, France; 6. Clinical and Epidemiological Research Unit, INSERM CIC1401, France)

OC46- WEIGHT VARIABILITY, PHYSICAL FUNCTIONING AND INCIDENT DISABILITY IN OLDER ADULTS. Katie McMenamin, Joshua F. Baker (Perelman School of Medicine at the University of Pennsylvania, USA)

OC47- EVALUATION OF THE VALUE OF THE SARQOL® QUESTIONNAIRE IN SCREENING FOR SARCOPENIA. Anton Geerinck¹, Bess Dawson-Hughes², Charlotte Beaudart¹, Médéa Locquet¹, Jean-Yves Reginster^1,3, Olivier Bruyère^1,4,5(1. Division of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, World Health Organization Collaborating Center for Public Health aspects of musculo-skeletal health and ageing; 2. Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA; 3. Chair for Biomarkers of Chronic Diseases, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia; 4. Department of Sport Rehabilitation Sciences, University of Liège, Belgium; 5. Physical, Rehabilitation Medicine and Sports Traumatology, SportS2, University Hospital of Liège, Belgium)

OC48- AN ELECTRONIC FRAILTY INDEX PREDICTS IN-HOSPITAL MORTALITY IN GERIATRIC PATIENTS. Jonathan K. L. Mak¹, Maria Eriksdotter^2,3, Laura Kananen^1,4, Ralf Kuja-Halkola¹, Anne-Marie Boström^3,5, Miia Kivipelto^2,3, Martin Annetorp^2,3, Carina Metzner^2,3, Sara Hägg¹, Viktoria Bäck Jerlardtz⁶, Malin Engström⁷, Peter Johnson⁸, Lars Göran Lundberg⁹, Elisabet Åkesson¹⁰, Carina Sühl Öberg¹¹, Maria Olsson^12,13, Tommy Cederholm^2,3,14, Dorota Religa^2,3, Juulia Jylhävä¹(1. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2. Division of Clinical Geriatrics, Department of Neurobiology, Care sciences and Society, Karolinska Institutet, Stockholm, Sweden; 3. Theme Inflammation and Aging, Karolinska University Hospital, Huddinge, Sweden; 4. Faculty of Social Sciences, Tampere University, Tampere, Finland; 5. Division of Nursing, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden; 6. Department of Geriatric Medicine, Jakobsbergsgeriatriken, Stockholm, Sweden; 7. Department of Geriatric Medicine, Sabbatsbergsgeriatriken, Stockholm, Sweden; 8. Department of Geriatric Medicine, Capio Geriatrik Nacka AB, Nacka, Sweden; 9. Department of Geriatric Medicine, Dalengeriatriken Aleris Närsjukvård AB, Stockholm, Sweden; 10. Research and Development Unit, Stockholms Sjukhem, Stockholm, Sweden; 11. Department of Geriatric Medicine, Handengeriatriken, Aleris Närsjukvård AB, Stockholm, Sweden; 12. Department of Geriatric Medicine, Capio Geriatrik Löwet, Stockholm, Sweden; 13. Department of Geriatric Medicine, Capio Geriatrik Sollentuna, Stockholm, Sweden; 14. Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden)

OC49- DOES SARCOPENIA INCREASE THE RISK OF TRANSITIONS IN FRAILTY STATUS? Alejandro Álvarez-Bustos¹, Jose Antonio Carnicero-Carreño^1,2, Francisco Javier Garcia-Garcia^1,4, Cristina Alonso-Bouzón^1,4, Leocadio Rodríguez-Mañas^1,4(1. Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; 2. Biomedical Research Foundation, Getafe University Hospital, Getafe, Spain; 3. Geriatrics Department, Virgen del Valle Hospital, Toledo, Spain; 4. Geriatrics Department, Getafe University Hospital, Getafe Spain)

OC50- CORRECTING FOR SUBCUTANEOUS ADIPOSE TISSUE MARGINALLY IMPROVES THE ASSOCIATION BETWEEN ULTRASOUND ECHO INTENSITY AND MAGNETIC RESONANCE PROTON DENSITY FAT FRACTION. Benjamin Rush¹, Sujay Garlapati¹, Jevin Lortie¹, Katie Osterbauer¹, TJ Colgan², Ken Lee², Brian Anthony³, Scott B. Reeder², Adam Kuchnia¹(1. Nutritional Sciences Department, University of Wisconsin-Madison, Madison, WI, USA; 2. Department of Radiology, University of Wisconsin-Madison, Madison, WI, USA; 3. Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA)

OC51- NEUROFILAMENT-LIGHT CHAINS (NF-L), A BIOMARKER OF NEURONAL DAMAGE, IS INCREASED IN SARCOPENIC PATIENTS: RESULTS OF THE SARCOPHAGE STUDY. Aurélie Ladang¹, S. Kovacs¹, L. Lengelé², M. Locquet², J.Y. Reginster^2,3, O. Bruyère^2,4, E. Cavalier¹(1. Clinical Chemistry department, CHU Liège; Belgium; 2. WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Division of Public Health, Epidemiology and Health Economics, University of Liège, Belgium; 3. Chair for Biomarkers of Chronic Diseases, Biochemistry Department, College of Science, King Saud University, Riyadh, KSA; 4. Physical, Rehabilitation Medicine and Sports Traumatology, SportS2, University Hospital of Liège, Belgium)

OC52- IMPROVEMENT IN FUNCTIONAL STATUS AT 2 YEARS IN PRE-FRAIL AND FRAIL OLDER PEOPLE WITH TYPE 2 DIABETES MELLITUS FOLLOWING A MULTIMODAL INTERVENTION-MIDFRAIL CLINICAL TRIAL. Olga Laosa^1,2, Laura Pedraza², Alan Sinclair³, Eva Topinkova⁴, Isabelle Bourdel-Marchasson⁵, Bruno Vellas⁶, Andrej Zeyfang⁷, Giuseppe Paolisso⁸, Mikel Izquierdo⁹, Leocadio Rodriguez Manas^1,10(1. Centre of Network Biomedical Research on Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain; Institute of Biomedical Research, University Hospital of Getafe, Getafe, Madrid, Spain; 2. Institute of Biomedical Research, University Hospital of Getafe, Getafe, Madrid, Spain; 3. fDROP and King's College, London, UK; 4. Department of Geriatrics, First Faculty of Medicine, Charles University, Prague, Czech Republic; 5. UMR 5536, Bordeaux University / CNRS; CHU Bordeaux, Bordeaux, France; 6. Gérontopõle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse, Toulouse, France; 7. Department of Internal Medicine, Geriatric Medicine, Palliative Medicine and Diabetology, medius Klinik OstfildernRuit, Germany; 8. Department of Advanced Medical and Surgical Sciences, University of Campania «Luigi Vanvitelli» Piazza Miraglia, Naples, Italy; 9. Navarrabiomed, Complejo Hospitalario de Navarra (CHN), Universidad Publica de Navarra (UPNA), IdiSNA, Pamplona, Spain; 10. Division of Geriatrics, University Hospital of Getafe, Getafe, Spain)

OC54- SOCIOECONOMIC POSITION AND RISK OF SARCOPENIA IN COMMUNITY-DWELLING OLDER ADULTS: FINDINGS FROM THE ENGLISH LONGITUDINAL STUDY OF AGEING. Lauren Swan¹, Austin Warters², Maria O'Sullivan¹(1. Department of Clinical Medicine, School of Medicine, Trinity College Dublin (TCD), Dublin 8, Ireland; 2. Older Person Services, Dublin North City and County Community Health Organisation, Health ServiceExecutive, Dublin 9, Ireland)

OC55- EFFECTS OF BODY COMPOSITION ON LONGITUDINAL GRIP STRENGTH IN CARDIOVASCULAR DISEASE PATIENTS FROM THE UK BIOBANK. Fayeza Ahmad, Rosie Fountotos, Aayushi Joshi, Jonathan Afilalo (Experimental Medicine, McGill University, Quebec, Canada; Clinical Epidemiology and Division of Cardiology, Jewish General Hospital, Quebec, Canada)

OC56- THE IMPACT OF A LIVE ONLINE EXERCISE TRAINING PROGRAM ON OLDER ADULTS' LEVELS OF PHYSICAL ACTIVITY: A PILOT RCT. Giulia Coletta¹, Angelica Mcquarrie¹, Julia Di Bussolo², Paula Bochnak², Stuart Phillips^1,2(1. Department of Kinesiology, McMaster University, Hamilton, ON, Canada; 2. Physical Activity Centre of Excellence, McMaster University, Hamilton, ON, Canada)

OC57- OSTEOSARCOPENIA PREDICTS MORTALITY IN OLDER ADULTS WITH SEVERE AORTIC STENOSIS UNDERGOING TRANSCATHETER VALVE REPLACEMENT. Pablo Solla^1,2, Julia Rodighiero¹, Neelabh Rastogi¹, Andrew Meng¹, Jonathan Afilalo¹(1. Division of Cardiology & Centre for Clinical Epidemiology. Jewish General Hospital, McGill University, Canada; 2. Division of Geriatric Medicine & Health Research Institute of Asturias (ISPA). Hospital Monte Naranco, Asturian, Health Service, Spain)

OC58- STUDY DESIGN AND RATIONALE FOR HERA: A PHASE I/II STUDY EVALUATING THE EFFECTS OF INTRAVENOUS DELIVERY OF LOMECEL-B ON VACCINE-SPECIFIC ANTIBODY RESPONSES IN SUBJECTS WITH AGING FRAILTY. Kevin N. Ramdas, Keyvan Yousefi, Geoff Green, Lisa Moss, Ben Hitchinson, Liliana Diaz, Jessica Protenic, Joshua M. Hare, Anthony A. Oliva, Jr. (Longeveron Inc., Miami, FL, USA)

OC59- EXPLORING EARLY DETECTION OF FRAILTY SYNDROME IN OLDER ADULTS: EVALUATION OF BIOMARKERS, CLINICAL PARAMETERS AND MODIFIABLE RISK FACTORS. Armanda Teixeira-Gomes^1,2,3,4, Filipa Esteves^1,2,4, Susana Silva², Vanessa Valdiglesias^1,5,6, Blanca Laffon^6,7, Joao Paulo Teixeira^1,2,4 Solange Costa^1,2,4(1. EPIUnit, Institute of Public Health, University of Porto, Porto, Portugal; 2. Environmental Health Department, National Institute of Health, Porto, Portugal; 3. ICBAS — Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Portugal; 4. Laboratory for Integrative and Translational Research in Population Health (ITR), Porto, Portugal; 5. Centro de Investigaciones Cientificas Avanzadas (CICA), Departamento de Biologia, Facultad de Ciencias, Universidade da Coruna, Grupo DICOMOSA, Campus A Zapateira, A Coruna, Spain; 6. Instituto de Investigacion Biomédica de A Coruna (INIBIC), AE CICA-INIBIC, A Coruna, Spain; 7. Centro de Investigaciones Cientificas Avanzadas (CICA), Departamento de Psicologia, Facultad de Ciencias de la Educacion, Universidade da Coruna, Grupo DICOMOSA, Campus Elvina, A Coruna, Spain)

OC60- COGNITIVE IMPAIRMENT PREDICTS SARCOPENIA AFTER NINE YEARS IN OLDER COMMUNITY-DWELLING BRAZILIANS. Gabriela Cabett Cipolli¹, Flavia Silva Arbex Borim^1,2, Deusivania Vieira Falcao³, Meire Cachioni^1,3, Ruth Caldeira de Melo³, Samila Sathler Tavares Batistoni^1,3, Ivan Aprahamia⁴, Anita Liberalesso Neri³, Monica Sanches Yassuda^1,3(1. State University of Campinas, Campinas, SP, Brazil; 2. University of Brasilia, Brasilia, DF, Brazil; 3. University of Sao Paulo, Sao Paulo, SP, Brazil; 4. Faculty of Medicine of Jundiai, Jundiai, SP, Brazil)

OC61- PREDICTORS AND FUNCTIONAL CONSEQUENCES OF LONG-COVID IN HOSPITALIZED PATIENTS: A PROSPECTIVE COHORT STUDY. Marlon Juliano Romero Aliberti, Murilo Bacchini Dias, Victor José Dornelas Melo, Wilson Jacob Filho, Thiago Junqueira Avelino-Silva (University of Sao Paulo Medical School, Brazil; and Research Institute, Hospital Sirio-Libanes, Sao Paulo, Brazil)

OC62- COMPUTED TOMOGRAPHY INTERNAL CALIBRATION FOR MUSCLE DENSITY ANALYSIS OF CRITICAL CARE PATIENTS. Ainsley C.J. Smith^1,2,3, Justin J. Tse^1,2,3, Steven K. Boyd^1,2,3, Sarah L. Manske^1,2,3(1. Biomedical Engineering Graduate Program, University of Calgary, Alberta, Canada; 2. Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada; 3. McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada)

OC63- ASSOCIATION OF NEUTROPHIL-TO-LYMPHOCYTE (NLR) RATIO WITH IN-HOSPITAL MORTALITY ACCORDING TOFRAILTY STATUS IN OLDER VETERANS HOSPITALIZED WITH COVID-19 INFECTION. Marlena Fernandez¹, Alma Diaz¹, Dominique Tosi², Victor Cevallos¹, Jorge G. Ruiz^1,2,3(1. Miami VAHS Geriatric Research, Education and Clinical Center (GRECC), USA; 2. University of Miami/Jackson Health System, USA; 3. University of Miami Miller School of Medicine, USA)

Late Breaking Communications

LB1- THIGH AND CALF MYOSTEATOSIS ARE STRONGLY ASSOCIATED WITH MUSCLE AND PHYSICAL FUNCTION IN AFRICAN CARIBBEAN MEN. Adam J. Santanasto¹, Joseph M. Zmuda¹, Ryan K. Cvejkus¹, Christopher L. Gordon², Sangeeta Nair³, J. Jeffrey Carr³, James G. Terry³, Victor W. Wheeler⁴, Iva Miljkovic¹(1. Department of Epidemiology, University of Pittsburgh, USA; 2. McMaster University, Hamilton, ON, Canada; 3. Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA; 4. Tobago Health Studies Office, Scarborough, Tobago, Trinidad & Tobago)

LB2- EVIDENCE FOR CELLULAR SENESCENCE IN SKELETAL MUSCLE AGING. Xu Zhang^1,2, Leena Habiballa^1,3,8, Zaira Aversa^1,2, Ayumi E. Sakamoto¹, Davis A. Englund^1,2, Vesselina M. Pearsall¹, Thomas A. White¹, Matthew M. Robinson⁴, Donato A. Rivas⁵, Surendra Dasari⁶, Yan Er Ng¹, Anthony B. Lagnado^1,7, Sarah K. Jachim¹, Antoneta Granic^3,8, Avan A. Sayer^3,8, Diana Jurk^1,7, Ian R. Lanza⁹, Sundeep Khosla^1,10, Roger A. Fielding⁵, K. Sreekumaran Nair¹⁰, Marissa J. Schafer^1,7, João F. Passos^1,7, Nathan K. LeBrasseur^1,2(1. Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA; 2. Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA; 3. NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; 4. School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA; 5. Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, Massachusetts, USA; 6. Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; 7. Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA; 8. AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK; 9. Division of Endocrinology, Mayo Clinic, Rochester, MN, USA; 10. Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA)

LB3- HIGH INTENSITY INTERVAL TRAINING (HIIT) ENHANCES PHYSICAL AND COGNITIVE PERFORMANCE AND OVERALL QUALITY OF LIFE IN OLDER VETERANS. Kenneth L. Seldeen, Yonas Redae, Ayesha Rahman, Nikhil Satchidanand, M. Jeffery Mador, and Bruce R. Troen (Division of Geriatrics and Palliative Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo and Research Service, Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA)

LB4- OUT OF HOSPITAL FRONT OF MIND: VIRTUAL HOSPITAL MODEL OF INTEGRATED CARE FOR FRAIL OLDER ADULTS. Michelle N Grinman^1,2,3, Azadeh Motehayerarani^1,2, Jillian Walsh^1,2,3, Lesly Deuchar¹, Lindsay Wodinski¹, Juhina El-Hajj¹, Vanessa Gibbons-Reid¹, Ryan Kozicky¹, Shy Amlani¹, Gregory Hrynchyshyn^1,4(1. Alberta Health Services, AB, Canada; 2. Cumming School of Medicine, University of Calgary, Calgary AB, Canada; 3. O'Brien Institute for Public Health, University of Calgary, Calgary AB, Canada; 4. Faculty of Medicine and Dentistry, University of Alberta, Edmonton AB, Canada)

LB5- THE DIET QUALITY AND NUTRITION INADEQUACY OF PRE-FRAIL OLDER ADULTS IN NEW ZEALAND: STAYING UPRIGHT AND EATING WELL RESEARCH, SUPER STUDY. Esther Tay, Ruth Teh, Daniel Barnett, Evelingi Leilua, Ngaire Kerse, Maisie Rowland, Anna Rolleston, Debra Waters, Richard Edlin, Martin Connolly, Leigh Hale, Avinesh Pillai (University of Auckland, Auckland, New Zealand)

LB6- ARNT REGULATES MUSCULAR ADAPTATION TO EXERCISE. Yori Endo, Mehran Karvar, Indranil Sinha (Harvard Medical School, Brigham and Women's Hospital, USA)

LB7- RATIO OF APPENDICULAR MUSCLE MASS TO TOTAL BODY FAT PREDICTIS ADVERSE OUTCOMES OF OLDER ADULTS: A POTENTIAL BIOMARKER OF SARCOPENIC OBESITY. Pei-Chin Yu^1,2,4, Wei-Ju Lee^2,3,5, Ming-Hsien Lin^1,3, Li-Ning Peng^1,2,3, Liang-Kung Chen^1,2,3,6(1. Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan; 2. Aging and Health Research Center, National Yang Ming Chiao Tung University, Hsin-Chu, Taiwan; 3. Department of Geriatric Medicine, National Yang Ming Chiao Tung University School of Medicine, Hsin-Chu, Taiwan; 4. Institute of Neuroscience, National Yang Ming Chiao Tung University, Hsin-Chu, Taiwan; 5. Department of Family Medicine, Taipei Veterans General Hospital Yuanshan Branch, Yi-Lan, Taiwan; 6. Taipei Municipal Gan-Dau Hospital, Taipei, Taiwane)

LB8- OPA1 ORCHESTRATES PRECOCIOUS SENESCENCE, DEGENERATION OF MULTIPLE ORGANS, AND PREMATURE DEATH THROUGH INFLAMMATION AND METABOLIC CHANGES. Caterina Tezze, Nicola Faedda, Ivan Francesco Amendolagine, Marco Sandri (University of Padua, Padova, Italy)

LB9- THE OUTCOMES FROM CARDIOPULMONARY RESUSCITATION IN ADULTS LIVING WITH FRAILTY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Joseph Hamlyn¹, Thomas Jackson², Carly Welch³(1. University of Birmingham, Birmingham, UK; 2. Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK; 3. Centre for Musculoskeletal Ageing, University of Birmingham, Birmingham UK)

LB10- HANDGRIP STRENGTH, BUT NOT SARC-F SCORE, PREDICTS COGNITIVE IMPAIRMENT IN OLDER ADULTS IN PRIMARY CARE SETTINGS. Paul KM Poon¹, KW Tam¹, Dexing Zhang¹, Benjamin HK Yip¹, Jean Woo², Samuel YS Wong¹(1. Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong Special Administrative Region; 2. Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region; Jockey Club Institute of Ageing, The Chinese University of Hong Kong, Hong Kong Special Administrative Region)

LB11- EFFECT OF VITAMIN D LEVELS ON 30-DAY MORTALITY IN OLDER ADULTS HOSPITALIZED WITH COVID-19 ACCORDING TO FRAILTY STATUS. Sanaa Badour¹, Marlena Fernandez², Victor Cevallos², Jorge G. Ruiz^1,2,3(1. University of Miami/Jackson Health System, USA; 2. Miami VAHS Geriatric Research, Education and Clinical Center (GRECC), USA; 3. University of Miami Miller School of Medicine, USA)

LB12- DIFFERENTIAL MODERATION OF APOE AND 5-HTTLPR GENOTYPES OVER SOCIAL VULNERABILITY IN PREDICTING MORTALITY AMONG COMMUNITY-DWELLING MIDDLE-AGED AND OLDER ADULTS: A NATIONWIDE POPULATION-BASED STUDY. Hsin-Yu Liu^1,2,3, Li-Ning Peng^1,3, Wei-Ju Lee^1,4, Ming-Yueh Chou⁵, Chih-Kuang Liang⁵, Ming-Hsien Lin^1,3, Liang-Kung Chen^1,3,6(1. Aging and Health Research Center, National Yang Ming Chiao Tung University Yangming Campus, Taipei, Taiwan; 2. Institute of Public Health, National Yang Ming Chiao Tung University Yangming Campus, Taipei, Taiwan; 3. Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan 4. Department of Family Medicine, Taipei Veterans General Hospital Yuanshan Branch, Yi-Lan, Taiwan; 5. Center for Geriatrics and Gerontology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 6. Taipei Municipal Gan-Dau Hospital, Taipei, Taiwan)

LB13- SARCOPENIA IN COMMUNITY-DWELLING OLDER ADULTS AT RISK OF MALNUTRITION: PREVALENCE AND ASSOCIATED FACTORS. Samuel Teong Huang Chew¹, Siew Ling Tey², Menaka Yalawar³, Zhongyuan Liu², Geraldine Baggs⁴, Choon How How^5,6, Magdalin Cheong⁷, Wai Leng Chow⁸, Yen Ling Low², Dieu Thi Thu Huynh², Ngiap Chuan Tan^6,9(1. Department of Geriatric Medicine, Changi General Hospital, Singapore; 2. Abbott Nutrition Research and Development, Asia-Pacific Center, Singapore; 3. Statistical Services, Cognizant Technologies Solution Pvt. Ltd. Mumbai, India; 4. Abbott Nutrition Research and Development, Columbus, Ohio, United States of America; 5. Care and Health Integration, Changi General Hospital, Singapore; 6. SingHealth-Duke NUS Family Medicine Academic Clinical Program, Singapore; 7. Department of Dietetic & Food Services, Changi General Hospital, Singapore 8. Health Services Research, Changi General Hospital, Singapore; 9. SingHealth Polyclinics, Singapores)

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