Prevalence of Physical Frailty: Results from the DO-HEALTH Study - 21/11/24
, P.O. Chocano-Bedoya 2, 3, L.A. Abderhalden 1, 2, G. Freystaetter 1, 2, A. Sadlon 1, 2, J.A. Kanis 4, 5, R.W. Kressig 6, S. Guyonnet 7, J.A.P. DaSilva 8, D. Felsenberg 9, R. Rizzoli 10, M. Blauth 11, E.J. Orav 12, A. Egli 2, H.A. Bischoff-Ferrari 1, 2, 13
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Abstract |
Background |
Frailty is a geriatric syndrome associated with multiple negative health outcomes. However, its prevalence varies by population and instrument used. We investigated frailty and pre-frailty prevalence by 5 instruments in community-dwelling older adults enrolled to a randomized-controlled trial in 5 European countries.
Methods |
Cross-sectional baseline analysis in 2,144 DO-HEALTH participants recruited from Switzerland, Austria, France, Germany, and Portugal with complete data for frailty. Frailty status was assessed by the Physical Frailty Phenotype [PFP], SOF-Frailty Index [SOF-FI], FRAIL-Scale, SHARE-Frailty Instrument [SHARE-FI], and a modified SHARE-FI, and compared by country, age, and gender. Logistic regression was used to determine relevant factors associated with frailty and pre-frailty.
Results |
Mean age was 74.9 (±4.4) years, 61.6% were women. Based on the PFP, overall frailty and pre-frailty prevalence was 3.0% and 43.0%. By country, frailty prevalence was highest in Portugal (13.7%) and lowest in Austria (0%), and pre-frailty prevalence was highest in Portugal (57.3%) and lowest in Germany (37.1%). By instrument and overall, frailty and pre-frailty prevalence was highest based on SHARE-FI (7.0% / 43.7%) and lowest based on SOF-FI (1.0% / 25.9%). Frailty associated factors were residing in Coimbra (Portugal) [OR 12.0, CI 5.30–27.21], age above 75 years [OR 2.0, CI 1.17–3.45], and female gender [OR 2.8, CI 1.48–5.44]. The same three factors predicted pre-frailty.
Conclusions |
Among relatively healthy adults age 70 and older enroled to DO-HEALTH, prevalence of frailty and pre-frailty differed significantly by instrument, country, gender, and age. Among instruments, the highest prevalence of frailty and pre-frailty was documented by the SHARE-FI and the lowest by the SOF-FI.
Le texte complet de cet article est disponible en PDF.Key words : Frailty, community-dwelling, prevalence, clinical trials, epidemiology
Plan
| Prof. Felsenberg is deceased Electronic Supplementary Material Supplementary material is available for this article at jfa.2021.18 and is accessible for authorized users. Copyright comment corrected publication in 2021 How to cite this article: M. Gagesch, P.O. Chocano-Bedoya, L.A. Abderhalden, et al. Prevalence of Physical Frailty: Results from the DO-HEALTH Study. J Frailty Aging 2022;11(1)18-25; jfa.2021.18 Incomplete funding information during original upload. |
Vol 11 - N° 1
P. 18-25 - janvier 2022 Retour au numéro
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