Association of Balance Impairment with Risk of Incident Dementia among Older Adults - 21/11/24
, Michelle J. Suh 4, Jee Young Suh 5, ⁎
Bienvenue sur EM-consulte, la référence des professionnels de santé.
Article gratuit.
Connectez-vous pour en bénéficier!
Abstract |
Background |
A growing body of data suggests that balance impairment may be linked to the onset of dementia.
Objectives |
However, a large-scale epidemiologic investigation is needed to clarify its association in older adults.
Design |
A retrospective-prospective hybrid database.
Setting |
Cox proportional hazards regression model was used to assess the relationship between balance impairment and the risk of incident dementia, and the results were provided as adjusted hazard ratios (aHR) with 95% confidence intervals (CI). All participants were tracked until the date of incident dementia, death, or 31 December 2019 whichever came first.
Participants |
We analyzed 143,788 older adults who had at least one health screening between 2009 and 2019 from the Korea National Health Insurance Service-Senior Cohort.
Measurements |
A total of 3,774 cases of dementia were discovered throughout 850,425 person-years of follow-up investigation. Balance impairment was associated with a risk of dementia compared to those without balance impairment (adjusted hazard ratio [aHR] 1.83; 95% CI, 1.69–2.00; P value <0.001).
Results |
Risks of the Alzheimer’s disease (aHR, 1.80; 95% CI, 1.65–1.96; P for trend <0.001) and the vascular dementia (aHR, 2.94; 95% CI, 1.89–4.58; P for trend <0.001) showed comparable trends and findings.
Conclusions |
Balance impairment was found to be independently associated with an increased risk of dementia in older adults.
Le texte complet de cet article est disponible en PDF.Key words : Postural balance, one-leg standing, public health, dementia, mass screening
Plan
| These authors contributed equally. Data Sharing We have not previously published or currently in press works stemming from this same dataset. The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request. |
Vol 11 - N° 1
P. 130-137 - janvier 2024 Retour au numéro
Article précédent
- Relationships of Hypnotics with Incident Dementia and Alzheimer’s Disease: A Longitudinal Study and Meta-Analysis
- J.-H. Hou, S.-L. Sun, C.-C. Tan, Y.-M. Huang, L. Tan, Alzheimer’s Disease Neuroimaging Initiative, Wei Xu
- High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer’s Disease Via a Specific Tau Phosphorylation Pattern
- Y. Ito, Shuko Takeda, T. Nakajima, A. Oyama, H. Takeshita, K. Miki, Y. Takami, Y. Takeya, M. Shimamura, H. Rakugi, Ryuichi Morishita
Bienvenue sur EM-consulte, la référence des professionnels de santé.