New guidelines reduce the risk of hospitalization for adult patients with uncomplicated Plasmodium falciparum malaria: An observational, multicenter, retrospective French study - 16/10/24
, Gilles Cottrell b, Michel Cot b, Fadi Hillary Minka c, f, Marc Thellier d, g, Christophe Choquet a, Sandrine Houze b, eHighlights |
• | In this study, we observed increased ambulatory care in uncomplicated malaria cases since the application of the new guidelines. |
• | Chemoprophylaxis was infrequent. |
• | With the introduction of artemisinin derivatives, the risk of hospitalization was gradually reduced. |
Abstract |
Objectives |
We aimed to evaluate the impact of malaria declaration year (before or after 2017) on the frequency of hospitalization in metropolitan France of patients with uncomplicated non-vomiting P.falciparum malaria.
Patients and methods |
An observational, multicenter, retrospective study was carried out, using the database from the French National Reference Centre for Malaria. Descriptive analysis and multivariate analysis by logistic regression were performed using the multiple imputation by chained equation method to handle missing data.
Results |
More than 2000 (2184) uncomplicated non-vomiting P.falciparum malaria cases were recorded. Our multivariate analysis showed an association between the year 2018 and reduced risk of hospitalization (OR: 0.89; 95% CI: 0.81–0.97).
Conclusion |
Compared to 2016, during 2018 we observed a trend toward ambulatory care for patients presenting with uncomplicated non-vomiting P.falciparum malaria.
Le texte complet de cet article est disponible en PDF.Keywords : Artemisinin derivatives, Hospitalization risk, Imported malaria, Plasmodium falciparum, Uncomplicated malaria
Plan
Vol 54 - N° 7
Article 104963- octobre 2024 Retour au numéro
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