Incident stroke in individuals with peripartum cardiomyopathy - 16/08/24
ABSTRACT |
Background |
Peripartum cardiomyopathy (PPCM), a form of heart failure with reduced ejection fraction (HFrEF) that occurs during the final month of pregnancy through the first 5 months postpartum, is associated with heightened risk for maternal morbidity and mortality. Stroke is a common complication of HFrEF but there is limited data on the incidence of stroke in PPCM.
Methods |
Using statewide, nonfederal administrative data from 2000 to 2015, we analyzed age-adjusted risk of stroke within 3 years after PPCM-associated pregnancies.
Results |
PPCM was associated with a greater than 4-fold increased risk of pregnancy-related stroke (aHR 4.7, 95% CI: 3.0-7.5). This risk was highest at the time of PPCM diagnosis but remained elevated in the first postpartum year.
Conclusion |
Our findings confirm the strong association between PPCM and stroke, with risk that persists throughout and after the peripartum period.
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| Drs. Jerome Jeffrey Federspiel, MD, PhD and Sarah Goldstein, MD served as guest editors for this manuscript. |
Vol 275
P. 138-140 - septembre 2024 Retour au numéro
Article précédent
- Corrigendum to “Right atrial dysfunction is associated with atrial arrhythmias in adults with repaired tetralogy of Fallot” [American Heart Journal Volume 263 (2023)141-150]
- Alexander C. Egbe, William R. Miranda, Malini Madhavan, Omar Abozied, Ahmed Younis, Marwan H. Ahmed, Heidi M. Connolly, Abhishek J. Deshmukh
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- Kathryn J. Lindley, Claire Barker, Zainab Mahmoud, Nandini Raghuraman, Patricia Lenzen, Rachel Meyers, Sarah Osmundson, Shi Huang, Ravi V. Shah, Victor G. Davila-Roman
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