Endometriosis is a chronic, systemic condition that predominates across the reproductive lifespan of individuals. People with endometriosis and chronic pelvic pain require treatment and long-term management from a range of specialists outside of gynaecology. When establishing our centre of excellence for endometriosis (Melbourne, Australia), our vision was to create a patient-centred, bespoke and accessible multidisciplinary clinic with coordination and ongoing support led by a specialist endometriosis nurse. In our first 12-months, our endometriosis nurses provided 388 episodes of care and referred to a diverse network of specialist and allied health providers (frequently, gynaecologists, pain specialists, women’s health general practitioners, pelvic floor physiotherapists, expert pelvic imaging providers and pain psychologists). We strongly believe that a nurse-led multidisciplinary clinic is a feasible and effective clinical model for endometriosis care.