This research examines palynomorph assemblages preserved in sediments of the Iberian Pyrite Belt (IPB) that host the Neves-Corvo massive sulfide deposit and its importance for mineral exploration. The sediments belong to the Neves Formation, characterized by black shales and minor occurrences of siltstones and cherts, indicative of reduced environmental conditions, favorable to sulfide deposition in a hydrothermal context dominated by submarine felsic volcanism and graben structures. Analysis was performed in barren drill holes (e.g., Monte Novo), as opposed to productive sectors with massive sulfide mineralization and/or stockwork vein networks (e.g., Lombador, Corvo and Semblana deposits) and favorable sectors like Algaré. The recovered palynological assemblages are assigned to the LN Miospore Biozone, indicating a Late Famennian (latest Strunian) age. Several characteristic species of this age are identified, such as Retispora lepidophyta and Verrucosisporites nitidus in close association with Densosporites spitbergensis, Dictyotriletes fimbriatus, Retusotriletes cf. incohatus, Retusotriletes crassus, Vallatisporites spp. (including V. pusillites, and V. verrucosus). Despite some palynomorphs showing signs of breakage, folding, and indistinctness, no significant preservation or diversity differences were noted between barren and mineralized areas. The high abundance of marine phytoplankton in all studied black shales indicates ecologically stressed setting, dominated by dysoxic to anoxic conditions in a distal marine setting with active felsic volcanism and hydrothermal mineralizing events during Late Famennian time. This geologic context correlates with other IPB deposits and the global latest Devonian anoxic Hangenberg event.