Advances in Sleep-Disordered Breathing in Children - 26/07/24

Doi : 10.1016/j.ccm.2024.03.004

Alex Gileles-Hillel, MD ^a,^b,^c,^d,^⁎ , Rakesh Bhattacharjee, MD, FRCPC, DABP(SM), CBSM, DBSM ^e, Michael Gorelik, MD ^f, Indra Narang, MBBCH, MD ^g,^h
^a Neonatal Pulmonology Service, Pediatric Pulmonary and Sleep Unit
^b Pediatric Division, Hadassah Medical Center, Jerusalem 911111, Israel
^c The Faculty of Medicine, Hebrew University of Jerusalem
^d The Wohl Translational Research Institute, Hadassah Medical Center, Kiryat Hadassah, Ein Kerem, Jerusalem 911111, Israel
^e Division of Respiratory Medicine, Department of Pediatrics, Rady Children’s Hospital, UCSD, San Diego, CA 92123, USA
^f Division of Pediatric Otolaryngology, Children’s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI 53226, USA
^g Division of Respiratory Medicine, Faculty Development and EDI, Department of Paediatrics, Translational Medicine, Research Institute, Hospital for Sick Children
^h Department of Paediatrics, University of Toronto, 51 Banff Road, Toronto M4S2V6, Canada

^∗Corresponding author. Pediatric Division, Hadassah Medical Center, Kiryat Hadassah, Ein Kerem, Jerusalem 911111, Israel.Pediatric DivisionHadassah Medical CenterKiryat HadassahEin KeremJerusalem911111Israel

Résumé

Pediatric sleep-disordered breathing disorders are a group of common conditions, from habitual snoring to obstructive sleep apnea (OSA) syndrome, affecting a significant proportion of children. The present article summarizes the current knowledge on diagnosis and treatment of pediatric OSA focusing on therapeutic and surgical advancements in the field in recent years. Advancements in OSA such as biomarkers, improving continuous pressure therapy adherence, novel pharmacotherapies, and advanced surgeries are discussed.

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Keywords : Sleep-disordered breathing, Obstructive sleep apnea, Biomarkers, Continuous positive airway pressure, Adenotonsillectomy