Pitfalls in definitions on respiratory viruses and particularities of Adenovirus infection in hematopoietic cell transplantation patients: Recommendations from the EBMT practice harmonization and guidelines committee - 20/07/24

Abstract |
In 2023, the EBMT Practice harmonization and Guidelines Committee partnered with the EBMT Infection Diseases Working Party (IDWP) to undertake the task of delivering best practice recommendations, aiming to harmonize by expert consensus, the already existing definitions and future epidemiological and clinical studies among centers of the EBMT network. To attain this objective, a group of experts in the field was convened. The workgroup identified and discussed some critical aspects in definitions of community-acquired respiratory viruses (CARV) and adenovirus (ADV) infections in recipient of hematopoietic cell transplant (HCT). The methodology involved literature review and expert consensus. For CARV, expert consensus focused on defining infection severity, infection duration, and establishing criteria for lower respiratory tract disease (LRTD). For ADV, the expert consensus focused on surveillance methods and the definitions of ADV infection, certainty levels of disease, response to treatment, and attributable mortality. This consensus workshop provided indications to EBMT community aimed at facilitating data collection and consistency in the EBMT registry for respiratory viral infectious complications.
Le texte complet de cet article est disponible en PDF.Keywords : Allogeneic hematopoietic cell transplantation (allo-HCT), Cellular therapy, Community acquired respiratory virus, Influenza, Respiratory syncytial virus (RSV), Parainfluenza virus, SARS-CoV-2, Human metapneumovirus, Lower respiratory tract disease, Adenovirus, Harmonization workshop, Best practice EBMT recommendations, Definitions
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Vol 72 - N° 3
Article 103461- septembre 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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