Whole-brain simulation of interictal epileptic discharges for patient-specific interpretation of interictal SEEG data - 20/07/24
, Julia Makhalova b, c, Maxime Yochum a, Christian-G. Bénar c, d, Maxime Guye e, Fabrice Bartolomei b, d, Fabrice Wendling a, Isabelle Merlet aAbstract |
In patients with refractory epilepsy, the clinical interpretation of stereoelectroencephalographic (SEEG) signals is crucial to delineate the epileptogenic network that should be targeted by surgery. We propose a pipeline of patient-specific computational modeling of interictal epileptic activity to improve the definition of regions of interest. Comparison between the computationally defined regions of interest and the resected region confirmed the efficiency of the pipeline. This result suggests that computational modeling can be used to reconstruct signals and aid clinical interpretation.
Le texte complet de cet article est disponible en PDF.Keywords : Drug-resistant epilepsy, Interictal epileptic discharge, Inverse problem, SEEG modeling, Neural mass models
Plan
Vol 54 - N° 5
Article 103005- septembre 2024 Retour au numéro
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