Isolated Hydronephrosis and Urinary Tract Infection by Two Years of Age: A Population-Based Study - 09/07/24
, Noga Yaniv, MHI, MSc 2, Shoval Shoham, MSc 2, Yael Borovitz, MD 1, Shelly Levi, MD 1, Daniel Landau, MD 1, 3, Amit Dagan, MD 1, 3Abstract |
Objective |
To evaluate the risk for urinary tract infection (UTI) in infants with isolated hydronephrosis (IH).
Study design |
A retrospective, population-based study including all infants insured by Clalit Health Services and followed from birth to age 2 years in 3 regions of central Israel. Infants were divided into 3 groups based on electronic medical record diagnoses by age 6 months: (1) control: no urological diagnosis; (2) IH; and (3) complicated urological diagnosis (CUD): any additional nephrological/urological diagnosis with/without HN. The primary outcome was a diagnosis of UTI in the first 2 years of life.
Results |
The cohort included 340 619 infants (52% male): 333 920 controls, 4369 with IH, and 2331 with CUD. Infants with IH were associated with a greater risk for UTI than control patients (17% vs 4%, P < .001). UTI risk for a male infant with IH was greater than for a female infant in the control group (12.6% vs 6.5%, P < .001). In a multivariable logistic regression analysis, both IH (OR 7.04; 95% CI 6.46-7.66) and CUD (OR 14.9; 95% CI 13.6-16.4) were independently associated with UTI.
Conclusion |
Infants with IH are at a greater risk for UTI in the first 2 years of life, supporting the recommendation for a high index of suspicion for UTI in this population.
Le texte complet de cet article est disponible en PDF.Keywords : congenital anomalies of the kidneys and urinary tract, vesicoureteral reflux
Abbreviations : CHS, CUD, EMR, HN, ICD-9, IH, US, UTI, VUR
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Vol 271
Article 114055- août 2024 Retour au numéro
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