Paget's disease of the breast: Presentation, treatment, and outcomes in a modern cohort - 17/04/24
, Rebecca Warburton a, b , Jin-Si Pao a, b , Carol Dingee a, b , Amy Bazzarelli a, b , Jieun Newman-Bremang a, b , Elaine McKevitt a, b, ⁎ Abstract |
Background |
Surgical management for Paget's disease (PD) of the breast is controversial. This study aims to assess outcomes of PD patients based on procedure type and determine the reliability of imaging in estimating disease extent.
Methods |
A retrospective review analyzed clinicopathologic data of PD patients between 2009 and 2022. Pre-operative imaging size (PIS) was compared to post-operative pathology size (PPS) looking at concordance.
Results |
Thirty patients had PD, 21 underwent total mastectomy (TM) and 9 breast conserving surgery (BCS). Seventeen patients (56.7 %) had a final diagnosis of invasive cancer (14 TM, 3 BCS), with no local recurrences. Only 6/19 (31.6 %) patients with positive findings on ultrasound/mammogram had concordance between PIS and PPS. There were no breast/chest wall recurrences with a median follow up of 35.9 months.
Conclusion |
Ultrasound and mammogram had poor concordance with pathological size. BCS is feasible in select patients. MRI may help guide management.
Le texte complet de cet article est disponible en PDF.Highlights |
• | PD patients with no alarming features can be considered for BCS. |
• | MRI can be beneficial in PD patients with negative mammogram and ultrasound. |
• | Ultrasound and mammogram underestimate disease extent in PD. |
Keywords : Paget's disease of breast, Pre-operative imaging, Treatment, Outcome
Plan
Vol 231
P. 18-23 - mai 2024 Retour au numéro
Article précédent
- Paget’s disease of the breast: Insights from imaging to guide surgical management
- Juliet C. Dalton, Jennifer K. Plichta
- Intraoperative teaching methods, models, and frameworks: A scoping review for surgical resident education
- Marie Schulze, Lucas Streith, Sam M. Wiseman
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