Strong cross immune responses against sarbecoviruses but not merbecoviruses in SARS-CoV-2 BA.5/BF.7-infected individuals with or without inactivated COVID-19 vaccination - 30/03/24
Doi : 10.1016/j.jinf.2024.106138
Lujia Sun 1
Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
Qiuhong Man 1, Hui Zhang
Department of Laboratory Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, China
Shuai Xia, Lu Lu
Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
Xinling Wang 2
Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China
Lize Xiong 2
Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, China
Shibo Jiang 2, ⁎ 
Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
∗Corresponding author.
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Highlights |
• | SARS-CoV-2-infected persons have strong cross immune response against sarbecovirus. |
• | SARS-CoV-2-infected persons have weak cross immune response against merbecovirus. |
• | Inactivated COVID-19 vaccination enhances immune response against sarbecovirus. |
• | People in a post-COVID-19 world may not be very sensitive to sarbecovirus infection. |
Plan
© 2024
The Author(s). Publié par Elsevier Masson SAS. Tous droits réservés.
Vol 88 - N° 4
Article 106138- avril 2024 Retour au numéro
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