Research progress of the effective active ingredients of Astragalus mongholicus in the treatment of diabetic peripheral neuropathy - 22/03/24
Abstract |
Diabetic peripheral neuropathy (DPN) is one of the most prevalent consequences of diabetes, with a high incidence and disability rate. The DPN’s pathogenesis is extremely complex and yet to be fully understood. Persistent high glucose metabolism, nerve growth factor deficiency, microvascular disease, oxidative stress, peripheral nerve cell apoptosis, immune factors, and other factors have been implicated in the pathogenesis of DPN. Astragalus mongholicus is a commonly used plant used to treat DPN in clinical settings. Its rich chemical components mainly include Astragalus polysaccharide, Astragalus saponins, Astragalus flavones, etc., which play a vital role in the treatment of DPN. This review aimed to summarize the pathogenesis of DPN and the studies on the mechanism of the effective components of Astragalus mongholicus in treating DPN. This is of great significance for the effective use of Chinese herbal medicine and the promotion of its status and influence on the world.
Le texte complet de cet article est disponible en PDF.Highlights |
• | The specific pathogenesis of diabetic peripheral neuropathy was summarized. |
• | The active components of Astragalus mongholicus have multi-target therapeutic effect on diabetic peripheral neuropathy. |
• | The toxicology and pharmacokinetics of the active components of Astragalus mongholicus were summarized. |
Keywords : Astragalus mongholicus, Active Ingredient of Astragalus Mongholicus, Diabetic peripheral neuropathy, Astragalus polysaccharides, Astragalus saponin, Astragalus flavone, Pharmacological mechanism
Plan
Vol 173
Article 116350- avril 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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