Prophylactic distal perfusion catheter and survival in patients with out-of-hospital cardiac arrest: Secondary analysis of the SAVE-J II study - 19/03/24
, Hayato Taniguchi, M.D., Ph.D. b, Takeru Abe, Ph.D. b, Ichiro Takeuchi, M.D., Ph.D. a, b, Akihiko Inoue, M.D., Ph.D. c, Toru Hifumi, M.D., Ph.D. d, Tetsuya Sakamoto, M.D., Ph.D. e, Yasuhiro Kuroda, M.D., Ph.D. fSAVE-J II study group
Abstract |
Purpose |
The effect of a prophylactic distal perfusion catheter (DPC) after extracorporeal cardiopulmonary resuscitation (ECPR) in patients with out-of-hospital cardiac arrest (OHCA) remains unclear. Therefore, we aimed to clarify the association between prophylactic DPC and prognosis in patients with OHCA undergoing ECPR.
Materials and methods |
A secondary analysis of the Study of Advanced Life Support for Ventricular Fibrillation with Extracorporeal Circulation in Japan (SAVE-J II) database was performed to compare groups of patients with and without prophylactic DPCs. A multivariate analysis of survival at discharge was performed using factors that were significant in the two-arm comparison.
Results |
A total of 2044 patients were included in the analysis after excluding those who met the exclusion criteria. Survival at discharge was observed in 548 (26.9%) patients. In total, 100 (4.9%) patients developed limb ischemia, among whom 14 (0.7%) required therapeutic intervention. Multivariate analysis showed that prophylactic DPC did not result in a significant difference in survival at discharge (odds ratio: 0.898 [0.652–1.236], p = 0.509).
Conclusions |
The implementation of prophylactic DPC after ECPR for patients with OHCA may not contribute to survival at discharge.
Le texte complet de cet article est disponible en PDF.Keywords : Extracorporeal cardiopulmonary resuscitation, Out-of-hospital cardiac arrest, Prophylactic distal perfusion catheter, Venoarterial-extracorporeal membrane oxygenation
Abbreviations : DPC, ECPR, IABP, ICU, OHCA, PCI, ROSC, SAVE-J II
Plan
Vol 78
P. 69-75 - avril 2024 Retour au numéro
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