Transfusion futility thresholds and mortality in geriatric trauma: Does frailty matter? - 22/02/24
Abstract |
Background |
Data on massive transfusion (MT) in geriatric trauma patients is lacking. This study aims to determine geriatric transfusion futility thresholds (TT) and TT variations based on frailty.
Methods |
Patients from 2013 to 2018 TQIP database receiving MT were stratified by age and frailty. TTs and outcomes were compared between geriatric and younger adults and among geriatric adults based on frailty status.
Results |
The TT was lower for geriatric than younger adults (34 vs 39 units; p = 0.03). There was no difference in TT between the non-frail, frail, and severely frail geriatric adults (37, 30 and 25 units, respectively, p > 0.05). Geriatric adults had higher mortality than younger adults (63.1% vs 45.8%, p < 0.01). Non-frail geriatric adults had the highest mortality (69.4% vs 56.5% vs 56.2%, p < 0.01).
Conclusions |
Geriatric patients have a lower TT than younger adults, irrespective of frailty. This may help improve outcomes and optimize MT utilization.
Le texte complet de cet article est disponible en PDF.Highlights |
• | More blood will not always improve survival. |
• | This point in number of units is a transfusion threshold (TT). |
• | The TT for geriatric patients is lower than the TT for nongeriatric patients. |
• | Among geriatric patients, the TT is not impacted by frailty. |
• | Outcomes for geriatric patients receiving MTP are worse than of younger adults. |
Keywords : Blood transfusion, Transfusion futility threshold, Geriatric, Frailty, TQIP
Plan
Vol 228
P. 113-121 - février 2024 Retour au numéro
Article précédent
- Social determinants of health in pediatric trauma: Associations with injury mechanisms and outcomes in the context of the COVID-19 pandemic
- Azalia Avila, Oliver B. Lao, Holly L. Neville, Brian K. Yorkgitis, Henry L. Chang, Keith Thatch, Donald Plumley, Shawn D. Larson, John W. Fitzwater, Michele Markley, Felipe Pedroso, Anne Fischer, Lindsey B. Armstrong, Robin T. Petroze, Christopher W. Snyder
- Patient perspectives on barriers to obtaining surgery for primary hyperparathyroidism: A qualitative review
- Walker Phillips, James Stallworth, Andrea Gillis, Brenessa Lindeman, Herbert Chen, Jessica Fazendin, Polina Zmijewski
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?