Specialist industries usually develop custom-made medical devices outside a medical structure at the request of a healthcare professional. Access to 3D-printing technology with dedicated softwares in hospitals allow surgeons to perform virtual surgery leading to safer and more precise surgery. The authors present the hybrid workflow that combined the skills of surgeons, engineers and manufacturers to create titanium custom-made cutting guide and implants to reconstruct the nasal bone after the resection of an intraosseous hemangioma. This process aimed to optimize pre-operative planning, to improve precision, to predict the esthetic results of reconstruction. Moreover, it leads to a reduction of manufacturing time and the overall costs of surgery and to achieve genuine custom-made care.