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RETRACTED: LC-MS based metabolic profiling and wound healing activity of a chitosan nanoparticle-loaded formula of Teucrium polium in diabetic rats - 11/11/23

Doi : 10.1016/j.biopha.2023.115626 
Mardi M. Algandaby a , Ahmed Esmat b , Mohammed Z. Nasrullah c , Nabil A. Alhakamy d, e, f , Ashraf B. Abdel-Naim c , Omar M. Rashad g , Sameh S. Elhady h, , Enas E. Eltamany i
a Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
b Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
c Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
d Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
e Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
f Mohamed Saeed Tamer Chair for Pharmaceutical Industries, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
g Department of Pharmaceutical Technology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt 
h Department of Natural Products, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia 
i Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia 41522, Egypt 

Corresponding author.

Résumé

This article has been retracted: please see Elsevier policy on Article Correction, Retraction and Removal ( article-withdrawal ).

This article has been retracted at the request of the Editor.

Post-publication, an investigation conducted on behalf of the journal by Elsevier's Research Integrity & Publishing Ethics team identified a concern around the authenticity of the following figures/image panels:

Figure 3A [Day 0, Untreated] from the current article and Figure 2A [Day 4, Positive Control] from the article published in Drug Delivery on which Nabil A. Alhakamy and Ashraf B. Abdel-Naim also appear as coauthors and which was available online prior to the current article having been submitted to Biomedicine & Pharmacotherapy appear to depict the same source image, but are described as representing different experimental samples.

Figure 3A [Day 0, Vehicle treated] from the current article and Figure 2A [Day 7, MLT] from the article published in Drug Delivery on which Nabil A. Alhakamy and Ashraf B. Abdel-Naim also appear as coauthors and which was available online prior to the current article having been submitted to Biomedicine & Pharmacotherapy appear to depict the same source image, but are described as representing different experimental samples.

Asfour, Hani Z., Nabil A. Alhakamy, Osama A. A. Ahmed, Usama A. Fahmy, Shadab Md, Mohamed A. El-Moselhy, Waleed Y. Rizg, Adel F. Alghaith, Basma G. Eid, and Ashraf B. Abdel-Naim. 2022. Enhanced Healing Efficacy of an Optimized Gabapentin-Melittin Nanoconjugate Gel-Loaded Formulation in Excised Wounds of Diabetic Rats. Drug Delivery 29 (1): 18921902. doi: 10717544.2022.2086943 .

Figure 3A [Day 0, Untreated] from the current article and Figure 1A [Day 10, Untreated Control] from Pharmaceutics on which Nabil A. Alhakamy and Ashraf B. Abdel-Naim also appear as coauthors and which was available online prior to the current article having been submitted to Biomedicine & Pharmacotherapy appear to depict the same source image, but are described as representing different experimental samples.

Asfour, Hani Z., Nabil A. Alhakamy, Osama A. A. Ahmed, Usama A. Fahmy, Mohamed A. El-moselhy, Waleed Y. Rizg, Adel F. Alghaith, Basma G. Eid, and Ashraf B. Abdel-Naim. 2022. "RETRACTED: Amitriptyline-Based Biodegradable PEG-PLGA Self-Assembled Nanoparticles Accelerate Cutaneous Wound Healing in Diabetic Rats" Pharmaceutics 14, no. 9: 1792. pharmaceutics14091792

Figure 3A [Day 0, Untreated] from the current article and Figure 5A [Day 3, Untreated Control] from Pharmaceutics on which Nabil A. Alhakamy and Ashraf B. Abdel-Naim also appear as coauthors and which was available online prior to the current article having been submitted to Biomedicine & Pharmacotherapy appear to depict the same source image, but are described as representing different experimental samples.

Alhakamy, Nabil A., Giuseppe Caruso, Anna Privitera, Osama A. A. Ahmed, Usama A. Fahmy, Shadab Md, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Basma G. Eid, Ashraf B. Abdel-Naim, and et al. 2022. "RETRACTED: Fluoxetine Ecofriendly Nanoemulsion Enhances Wound Healing in Diabetic Rats: In Vivo Efficacy Assessment" Pharmaceutics 14, no. 6: 1133. pharmaceutics14061133

The authors were requested to provide comment on these concerns, as well as the original unprocessed image files to aid investigation.

It was felt that the explanation provided were unsatisfactory in resolving these concerns.

The Editor has lost confidence in the results and conclusions of the article and has determined it should be retracted.

The authors disagree with the retraction and dispute the grounds for it.

Le texte complet de cet article est disponible en PDF.

© 2023  The Authors. Publié par Elsevier Masson SAS. Tous droits réservés.
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