This article provides an overview of the World Professional Association of Transgender Health (WPATH) Standard of Care 8th edition (SOC8) chapter on transgender and gender diverse (TGD) prepubescent children (see Scott Leibowitz’s article, “Assessment of Transgender and Gender Diverse Adolescents: Incorporating the Standard of Care 8th Edition,” in this issue). This is the first WPATH SOC chapter in history, specifically devoted to children, acknowledging that the developmental needs and experiences of these youth can be distinguished from those of TGD adolescents. The child standards are based on the consensus of a range of expert authors and a broader consensus derived from a Delphi process involving the entire international interdisciplinary SOC8 authorship. The child SOC draw upon general developmental literature and employ an ecological framework to establish practice recommendations, including an assessment framework which engages family members and community outreach as warranted. The primary authors of the Child chapter of the SOC 8 include the following: Amy Tishelman, Ph.D. (lead author); Dianne Berg, Ph.D., Laura Edwards-Leeper, Ph.D., Diane Ehrensaft, Ph.D.; Susie Green, Aron Janssen, M.D., Jiska Ristori, Psy.D., Thomas Steensma, Ph.D., and John Strang, Psy.