The effect of vitamin D3 supplementation on atrial fibrillation in generally healthy men and women: The Finnish Vitamin D Trial - 13/09/23
Doi : 10.1016/j.ahj.2023.05.024
Jyrki K. Virtanen, PhD a, ⁎ 
, Sari Hantunen, PhD a, Christel Lamberg-Allardt, PhD b, JoAnn E. Manson, MD, DrPH c, d, Tarja Nurmi, PhD a, Matti Uusitupa, MD, PhD a, Ari Voutilainen, PhD a, Tomi-Pekka Tuomainen, MD, PhD a
, Sari Hantunen, PhD a, Christel Lamberg-Allardt, PhD b, JoAnn E. Manson, MD, DrPH c, d, Tarja Nurmi, PhD a, Matti Uusitupa, MD, PhD a, Ari Voutilainen, PhD a, Tomi-Pekka Tuomainen, MD, PhD a a Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
b Department of Food and Nutrition, University of Helsinki, Helsinki, Finland
c Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States
d Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States
⁎Reprint requests: Jyrki K. Virtanen, PhD, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland.Institute of Public Health and Clinical NutritionUniversity of Eastern FinlandP.O. Box 1627Kuopio70211Finland
Résumé |
Atrial fibrillation is a common cardiac arrhythmia with high morbidity risk. Observational studies suggest that vitamin D deficiency is associated with higher atrial fibrillation risk but there is limited evidence whether vitamin D supplementation could affect the risk. In these post hoc analyses from the Finnish Vitamin D Trial, we compared the incidence of atrial fibrillation with 5-year supplementation of vitamin D3 (1600 IU/d or 3200 IU/d) vs placebo.
Clinical Trial Registry number |
ClinicalTrials.gov: NCT01463813, NCT01463813
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© 2023
Publié par Elsevier Masson SAS.
Vol 264
P. 177-182 - octobre 2023 Retour au numéro
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