Securement of Umbilical Venous Catheter Using Cyanoacrylate Glue: A Randomized Controlled Trial - 08/09/23
, Giorgia Prontera, MD 1, Giovanni Pinna, MD 2, Francesco Cota, PhD 1, Simona Fattore, MD 1, Simonetta Costa, PhD 1, Martina Migliorato, MD 1, Giovanni Barone, MD 3, Mauro Pittiruti, MD 4, Giovanni Vento, MD 1Abstract |
Objective |
To evaluate the role of cyanoacrylate glue in reducing dislodgement of umbilical venous catheters (UVCs).
Study design |
This was a single-center, randomized, controlled, nonblinded trial. All infants requiring an UVC according to our local policy were included in the study. Infants with a UVC with a centrally located tip as verified by real-time ultrasound examination were eligible for the study. Primary outcome was the safety and efficacy of securement by cyanoacrylate glue plus cord-anchored suture (SG group) vs securement by suture alone (S group), as measured by reduction in dislodgment of the external tract of the catheter. Secondary outcomes were tip migration, catheter-related bloodstream infection, and catheter-related thrombosis.
Results |
In the first 48 hours after UVC insertion, dislodgement was significantly higher in the S group than in the SG group (23.1% vs 1.5%; P < .001). The overall dislodgement rate was 24.6% in the S group vs 7.7% in the SG group (P = .016). No differences were found in catheter-related bloodstream infection and catheter-related thrombosis. The incidence of tip migration was similar in both groups (S group 12.2% vs SG group 11.7%).
Conclusions |
In our single-center study, cyanoacrylate glue was safe and effective for securement of UVCs, and particularly effective in decreasing early catheter dislodgments.
Trial registration |
UMIN-CTR Clinical Trial; Registration number: R000045844.
Le texte complet de cet article est disponible en PDF.Abbreviations : CAJ, CRBSI, NICU, UVC
Plan
Vol 260
Article 113517- septembre 2023 Retour au numéro
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